Results 151 to 160 of about 1,063,279 (256)

Real‐world insights on switching aflibercept dosage for enhanced outcomes in age‐related macular degeneration (RISE‐AMD): Safety data

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate real‐world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age‐related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals, patients with nAMD at a Danish tertiary retina clinic were systematically switched to aflibercept 8 mg ...
Mary Graciya Karunainathan, Celine Lee, Kaweh Daniel Zohalinejad, Mads Odgaard Mæng, Nanna Würtz Fabrin, Sigurrós Jónsdóttir, Anne Kjærsgaard Hassing, Søren Kveiborg Yde, Charles C. Wykoff, Henrik Vorum, Yousif Subhi, Marie Ørskov, Lasse Jørgensen Cehofski   +12 more
wiley   +1 more source

Phase coupling between eye and brain pulsations is bidirectional and modulated by the parasympathetic system – An fMREye study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen, Väyrynen Tommi, Huotari Niko, Saarela Ville, Honkamo Marja, Helakari Heta, Järvelä Matti, Korhonen Vesa, Raitamaa Lauri, Kiviniemi Vesa   +9 more
wiley   +1 more source

Radial outer retina reflectivity (RORR) sign in LAMP2‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the radial outer retina reflectivity (RORR) sign in patients carrying pathogenic variants in the X‐linked lysosome‐associated membrane protein‐2 (LAMP2) gene and to review the histologic characteristics of LAMP2 expression in the human retina.
Rachael C. Heath Jeffery, Bohdan Kousal, Ulrike Grünert, Christine A. Curcio, Svetlana Cherepanoff, Tina M. Lamey, Michel Michaelides, Chrysanthi Tsika, Isabelle Chow, Omar A. Mahroo, Seungmin Lee, Martin Meliska, Milos Kubanek, Jakub Sikora, Siying Lin, Raymond C. B. Wong, Petra Liskova, Fred K. Chen   +17 more
wiley   +1 more source

En face localization of retinal telangiectatic capillaries using OCT compared with ICG angiography in chronic vascular macular oedema

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinal telangiectatic capillaries (TelCaps) are microvascular abnormalities associated with chronic vascular macular oedema and suboptimal response to intravitreal therapy. Targeted laser photocoagulation is beneficial but requires precise localization using indocyanine green angiography (ICG‐A), the reference standard. However, ICG‐A
Lucas Unger, Bénédicte Dupas, Mohamed Bennani, Daniela Castro Farias, Jean‐François Girmens, Aude Couturier, Michel Paques, Marie‐Noëlle Delyfer   +7 more
wiley   +1 more source

OCT angiography - new views of the retina

, 2018
Introduction: Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging technique that generates volumetric angiography images in a matter of seconds.
Minev, Ivaylo; Department of Medicine, Medical University of Varna, Mitova, Daniela; St. Petka Eye Clinic, Varna, Zhelezova, Veronika; Department of Medicine, Medical University of Varna, Ivanova, Desislava; Department of Medicine, Medical University of Varna, Gunev, Todor; Department of Medicine, Medical University of Varna   +4 more
core   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

OCT Angiography of Treatment-Naive Quiescent Choroidal Neovascularization inPachychoroid Neovasculopathy

, 2017
Purpose To estimate the prevalence of treatment-naïve quiescent choroidal neovascularization (CNV) among eyes with pachychoroid neovasculopathy and to investigate the OCT angiography (OCT-A) features. Design Prospective case series.
Carnevali Adriano, Sacconi Riccardo, Querques L., Querques Lea, Sacconi R., Scorcia V., Bandello F., Souied Eric, Marchese Alessandro, Querques Giuseppe, Scorcia Vincenzo, Capuano Vittorio, Souied E., Capuano V., Rabiolo A., Marchese A., Carnevali A., Querques G., RABIOLO A, Bandello Francesco   +19 more
core   +1 more source

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source

Inter‐eye microvascular asymmetry across stages of diabetic retinopathy: An OCT angiography study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate inter‐eye asymmetry in macular microvascular parameters across different stages of diabetic retinopathy (DR) using OCT angiography, and to explore the associations with clinical factors. Methods This cross sectional study included 442 eyes of 221 patients with diabetes mellitus type 2. Central subfield thickness (CST), area
Stela Vujosevic, Sema Tamer Kaderli, Gabriele Piccoli, Elena Tagliabue, Camilla Alovisi, Vanda Bucceri, Emanuele Torti, Elisa Marenzi, Dogukan Ozen, Livio Luzi, Paolo Nucci   +10 more
wiley   +1 more source

The Use of OCT and OCT Angiography in Detecting an Atypical Case of Retinal Capillary Hemangioma

, 2019
Retinal capillary hemangioma (RCH) is a benign retinal tumor defined by a vascular proliferation localized in the peripheral retina, juxtapapillary retina, or the intraneural portion of the optic nerve.
Luisa Pierro, Marco Gagliardi, Arrigo, Alessandro, Gagliardi, Marco, Brambati, Maria, Maria Brambati, Bandello, Francesco, Francesco Bandello, Pierro, Luisa, Alessandro Arrigo   +9 more
core   +1 more source