Results 171 to 180 of about 1,063,279 (256)

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Research Review: A scoping review exploring the needs, barriers, and facilitators to the collection of biological data in adolescence for mental health research

Journal of Child Psychology and Psychiatry, EarlyView.
Background There is increasing recognition of the challenge of representativeness in data, including economic, social, and ethnic diversity, in biological mental health research. This is a particular challenge in adolescence, where brain and body development are impacted by the environment.
Courtney Worrell, Camila Ribeiro Perez, Sorcha Alford, Rebecca Pollard, Luca Sforzini, Cole Sommeling, James Hotham, Amanda Rodney, Zara Sadiq, Hana Shah, Tyler Weetman, Gillian Brooks, Matthew R. Broome, Niyah Campbell, Nzinga Gardner, Seeromanie Harding, Anna Lavis, Rosemary R.C. McEachan, Valeria Mondelli, Craig Morgan, Kierra Morris, Chiara Nosarti, Talya Porat, David Ryan, Katy Shire, Anthony Woods, Carmine M. Pariante, CELEBRATE Youth Expert Working Group, Paola Dazzan, Rachel Upthegrove   +29 more
wiley   +1 more source

Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li, Rui Liang, Birong Dong, Lunxu Liu, Ning Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +6 more
wiley   +1 more source

Comparison between OCT angiography and fluorescein angiography on diabetic macular ischemia diagnosis

, 2016
The purpose of this study is to compare fluorescein angiography and optical coherence tomography (OCT) angiography images of foveal avascular zone (FAZ) in patients with diabetic retinopathy (DR) with and without diabetic macular ischemia.
Garcia, José Mauricio Botto de Barros
core  

Plasma ADAMTS13 activity in healthy dogs and dogs with chronic enteropathy

Journal of Small Animal Practice, EarlyView.
Objectives A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 is a von Willebrand factor cleaving enzyme that is associated with prothrombotic/hypercoagulable states in humans. In people, A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 activity is reduced with inflammatory bowel disease ...
S. I. Barth, S. M. DeMonaco, B. J. Conner, P. B. S. Serpa, A. R. Wilkinson   +4 more
wiley   +1 more source

Role of optical coherence tomography in posterior segment eye disorders: A review of two cases

Nigerian Postgraduate Medical Journal, 2014
Optical Coherence Tomography produces high resolution tomographic in in vivo imaging of biological tissues. The study reviews OCT images of two patients with varied retinal pathologies to determine its usefulness in aiding evaluation and management of ...
O M Uhumwangho, I Njinaka
doaj  

Mechanical pressure on endothelial cells mediates remote ischaemic preconditioning‐induced neuroprotection via miR‐126

Experimental Physiology, EarlyView.
Abstract Remote ischaemic preconditioning (RIPC) uses brief limb ischaemia to protect distant organs, but the mechanism of travel of the protective signal remains unclear. This study investigated whether endothelial cells (ECs) contribute to RIPC‐induced neuroprotection and the underlying mechanisms.
Xiaojie Wang, Lei Yan, Hongwei Zhu, Yifan Li, Qi Liu, Wei Li, Kerui Gong, Zhijun Zhao, Chunyang Zhang, Gang Fu, Guo Shao, Xunming Ji   +11 more
wiley   +1 more source

Project Sickle Cure: A Prospective, International Observational Study of Hematopoietic Cell Transplantation for Sickle Cell Disease

European Journal of Haematology, Volume 117, Issue 4, Page 1052-1060, October 2026.
ABSTRACT Background Sickle cell disease (SCD) is a chronic and life‐limiting hemoglobin and systemic vascular disease. While over 1000 people have undergone hematopoietic cell transplantation (HCT) over the last 40 years, long‐term disease‐specific and health‐related quality of life data are lacking.
Gregory M. T. Guilcher, Allistair Abraham, Staci D. Arnold, Christine Camacho‐Bydume, Jenny Duong, Scott Gillespie, Ann Haight, Monica L. Hulbert, Naresh Kumar, Katie Liu, Cherry Mammen, Aleksandra Mineyko, Abra Morgan, Alexander Ngwube, Robert S. Nickel, Araby Roberts, Fiona Schulte, Stephen Sands, Akshay Sharma, John T. Horan, Elizabeth O. Stenger   +20 more
wiley   +1 more source

A 7‐mm Covered TIPS Reduces Hepatic Encephalopathy Without Increasing Rebleeding in Cirrhotic Patients With Small Liver: A Randomized Study

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background/Aims International guidelines recommend initiating transjugular intrahepatic portosystemic shunt (TIPS) placement with an 8‐mm stent. However, there is an evident lack of randomized controlled trials evaluating TIPS diameters < 8 mm in cirrhotic patients with a relatively small liver. The aim of this study was to determine whether 7 
Fuquan Liu, Kan Zhang, Yu Zhang, Quanwei He, Mingming Meng, Xuemei Ma, Bing Zhu, Yifan Wu, Linjing An, Yifan Lv, Fuhuang Lin, Ke Zhang, Bowen Liu, Xiujuan Chang, Huiguo Ding, Jiangtao Liu, Yan Chen, Yongping Yang   +17 more
wiley   +1 more source

Distinct ocular microvascular alterations in Alzheimer's disease and cerebral small vessel disease

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION While both Alzheimer's disease (AD) and cerebral small vessel disease (CSVD) involve vascular dysfunction, the ocular microvascular differences between them remain largely underinvestigated. METHODS This cross‐sectional study included 650 participants (149 AD, 276 CSVD, and 225 cognitively unimpaired individuals).
Ziyi Zhang, Le Cao, Peng Liu, Shiyun Yang, Yuying Yan, William Robert Kwapong, Ying He, Mingyuan Yang, Hang Wang, Youjie Wang, Zijuan Feng, Jingyu Zhou, Ming Liu, Peng Lei, Bo Wu, Shuting Zhang   +15 more
wiley   +1 more source