Blue-blocking spectacles lenses for retinal damage protection and circadian rhythm: evaluation parameters [PDF]
arXiv, 2018 There is evidence for the effect of blue light on circadian cycle and ocular pathologies. Moreover, the introduction of LED lamps has increased the presence of blue light. In the last two years, many different blue blocking ophthalmic lenses have been introduced.
arxiv
A mass and solute balance model for tear volume & osmolarity in the normal and the dry eye [PDF]
, 2010 Tear hyperosmolarity is thought to play a key role in the mechanism of dry eye, a common symptomatic condition accompanied by visual disturbance, tear film instability, inflammation and damage to the ocular surface.
Bron, A J +3 more
core +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Ocular Disease Classification Using CNN with Deep Convolutional Generative Adversarial Network [PDF]
Lecture Notes in Electrical Engineering, vol 1190. Springer,
Singapore. 29 September 2024The Convolutional Neural Network (CNN) has shown impressive performance in image classification because of its strong learning capabilities. However, it demands a substantial and balanced dataset for effective training. Otherwise, networks frequently exhibit over fitting and struggle to generalize to new examples.
arxiv +1 more source
Advancing the stimuli response of polymer-based drug delivery systems for ocular disease treatment
, 2020 The development of efficient therapies for ocular diseases remains a significant challenge because of the static and dynamic barriers in the eye. A variety of pharmaceutical strategies have been explored to overcome these ocular physiological barriers ...
D. D. Nguyen, J. Lai
semanticscholar +1 more source
Rules for the Cortical Map of Ocular Dominance and Orientation Columns [PDF]
, 1994 Three computational rules are sufficient to generate model cortical maps that simulate the interrelated structure of cortical ocular dominance and orientation columns: a noise input, a spatial band pass filter, and competitive normalization across all ...
Grossberg, Stephen, Olsen, Stephen J.
core +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Ocular Drug Delivery: Role of Degradable Polymeric Nanocarriers for Ophthalmic Application
International Journal of Molecular Sciences, 2018 Ocular drug delivery has been a major challenge for clinical pharmacologists and biomaterial scientists due to intricate and unique anatomical and physiological barriers in the eye.
Cheng-Han Tsai +5 more
semanticscholar +1 more source
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
FEBS Open Bio, EarlyView.The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao +4 more
wiley +1 more source
Fully Convolutional Networks for Monocular Retinal Depth Estimation and Optic Disc-Cup Segmentation [PDF]
arXiv, 2019 Glaucoma is a serious ocular disorder for which the screening and diagnosis are carried out by the examination of the optic nerve head (ONH). The color fundus image (CFI) is the most common modality used for ocular screening.
arxiv