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Sporotrichosis is a subacute or chronic mycosis predominant in tropical and subtropical regions. It is an infection of subcutaneous tissue caused by Sporothrix fungus species, but occasionally resulting in an extracutaneous condition, including osteoarticular, pulmonary, nervous central system, and ocular disease.
Max Carlos Ramírez-Soto +2 more
openaire +5 more sources
AbstractOphthalmic diseases include both those analogous to systemic diseases (eg, inflammation, infection, neuronal degeneration) and not analogous (eg, cataract, myopia). Many anterior segment diseases are treated pharmacologically through eye drops, which have an implied therapeutic index of local therapy.
Gary D. Novack, Alan L. Robin
openaire +4 more sources
Microorganisms and Common Ophthalmic Diseases [PDF]
The human eye is in constant contact to environmental conditions that increase its likelihood in being exposed to a multitude of pathogens. Studies have revealed that the normal microbial flora found around the ocular area contribute to the well-being of
Su CW, Tighe S
core +1 more source
Surfactant protein D contributes to ocular defense against Pseudomonas aeruginosa in a murine model of dry eye disease. [PDF]
Dry eye disease can cause ocular surface inflammation that disrupts the corneal epithelial barrier. While dry eye patients are known to have an increased risk of corneal infection, it is not known whether there is a direct causal relationship between ...
Evans, David +4 more
core +7 more sources
Perceived Vertical and Lateropulsion: Clinical Syndromes, Localization, and Prognosis [PDF]
We present a clinical classification of central vestibular syndromes according to the three major planes of action of the vestibulo-ocular reflex: yaw, roll, and pitch.
Brandt +3 more
core +1 more source
Amaurosis Fugax: A Rare Oxaliplatin-Induced Ocular Toxicity – A Report of Three Cases
Oxaliplatin, a third-generation platinum-based agent, is a constitutive part of systemic treatment for colorectal cancer in adjuvant and metastatic settings. Ocular toxicity is an extremely rare adverse effect of Oxaliplatin.
Mutahar Ali Tunio +2 more
doaj +1 more source
Preparation and Ex-vivo Ocular delivery of Thermo-responsible pluronic F- 127 hydrogel containing Propranolol hydrochloride- loaded Liposomes [PDF]
Objective(s): Poor bioavailability of ophthalmic drops is mainly due to rapid nasolacrimal drainage and eye impermeability of corneal epithelium. The main aim of this study is to prepare a liposomal hydrogel for the ocular delivery of propranolol ...
Behzad Sharif MakhmalZadeh +2 more
doaj +1 more source
A combination of in situ gelling systems and a loaded drug self-assembling nanomicellar carrier was chosen in this study as a new potential Ocular Drug Delivery System (ODDS) for Cyclosporine-A (CyA), a poorly water-soluble drug.
Eleonora Terreni +5 more
doaj +1 more source
Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage [PDF]
Producción CientíficaLimbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss, chronic pain,
Calonge Cano, Margarita +7 more
core +2 more sources

