Results 61 to 70 of about 497,699 (317)

Ocular Manifestations in Pediatric Traumatic Brain Injury Admitted to the ICU: A Prospective Analysis

Vision
Background: Traumatic Brain Injury (TBI) in children is a major cause of morbidity and mortality worldwide. Ocular manifestations are common but often overlooked, despite their potential to cause long-term visual impairment.
Amer Jaradat, Rami Al-Dwairi, Adam Abdallah, Atef F. Hulliel, Rawhi Alshaykh, Mahmood Al Nuaimi, Ala’ Al Barbarawi, Seren Al Beiruti, Abdelwahab Aleshawi   +8 more
doaj   +1 more source

Modulation of CD44 Activity by A6-Peptide

Frontiers in Immunology, 2015
Hyaluronan (HA) is a nonsulfated glycosaminoglycan distributed throughout the extracellular matrix that plays a major role in cell adhesion, migration, and proliferation. CD44, a multifunctional cell surface glycoprotein, is a receptor for HA.
Malcolm eFinlayson
doaj   +1 more source

Ocular Nanomedicine

Advanced Science, 2022
Intrinsic shortcomings associated with conventional therapeutic strategies often compromise treatment efficacy in clinical ophthalmology, prompting the rapid development of versatile alternatives for satisfactory diagnostics and therapeutics.
Zhimin Tang, Xianqun Fan, Yu Chen, Ping Gu   +3 more
doaj   +1 more source

Clinical signs in neuro-ophthalmology: Eye signs in myasthenia gravis

Annals of Indian Academy of Neurology, 2022
A hallmark of myasthenia gravis (MG) is the variability and fatigability of striated muscles. The majority of people with MG have eye symptoms of ptosis and diplopia.
Sui Hsien Wong
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Visual Morbidity in Ocular Tuberculosis - Collaborative Ocular Tuberculosis Study (COTS)-1: Report #6

, 2021
Objective Aim of the study was to examine extent, natural history, and clinical features associated with visual impairment (VI) in patients diagnosed with ocular tuberculosis (OTB) by the Collaborative Ocular Tuberculosis Study (COTS)-1.
Bansal, Reema, Agrawal, Rupesh, Sharma, Aman, Moharana, Bruttendu, Bodaghi, Bahram, Pavesio, Carlos, Teoh, Stephen, Al-Dhibi, Hassan, Singh, Ramandeep, Gupta, Vishali, Chee, Soon-Phaik, Invernizzi, Alessandro, Kempen, John H., Lee, Richard, Mahajan, Sarakshi, Gunasekeran, Dinesh Visva, Vala, Ruchi, Tugal-Tutkun, Ilknur, Sharma, Kusum, Westcott, Mark, Barisani-Asenbauer, Talin, Narain, Shishir, Tasiopoulou, Anastasia, Zierhut, Manfred, Murthy, Somasheila, Gonzalez-Lopez, Julio J., Biswas, Jyotirmay, Kon, Onn Min, Babu, Kalpana, Cunningham, Emmett T., Goldstein, Debra A., Agarwal, Mamta, Jones, Nicholas, Basu, Soumayava, Androudi, Sofia, Agarwal, Aniruddha, Quan Dong Nguyen, Quan Dong Nguyen, Aggarwal, Kanika, Abraham, Sharanaya, Nadarajah, Sengal, Mahendradas, Padmamalini, Herbort, Carl P., Carreno, Ester, Mccluskey, Peter, Testi, Ilaria, Agarwal, Manisha, Cimino, Luca, Khairallah, Moncef, Raje, Dhananjay, Degli Esposti, Simona, Ho, Su Ling   +50 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Topographic relations between ocular dominance and orientation columns in the cat striate cortex

, 1988
Löwel S, Bischof H-J, Leutenecker B, Singer W. Topographic relations between ocular dominance and orientation columns in the cat striate cortex. Experimental Brain Research.
Leutenecker, B., Löwel, Siegrid, Bischof, Hans-Joachim, Singer, W.   +3 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source