Results 81 to 90 of about 804,614 (310)
Journal of Extracellular VesiclesWith an evolving understanding and new discoveries in extracellular vesicle (EV) biology and their implications in health and disease, the significant diagnostic and therapeutic potential of EVs for vision research has gained recognition.
Sun Young Lee +19 more
doaj +1 more source
Frontiers in MaterialsMicroemulsions (μEs) are more effective than conventional formulations for ophthalmic use due to their optical transparency, thermodynamic stability, structural flexibility and higher bioavailability.
Sehrish Zafar +8 more
doaj +1 more source
Awareness of treatment: a source of bias in subjective grading of ocular complications [PDF]
, 2019 Purpose: Bias has been described as one important obstacle in scientific research. The aim of this study was to explore “awareness of treatment” as a possible source of bias in subjective grading of ocular complications.
Cardona Torradeflot, Genís +1 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
High expression of PD-1 and PD-L1 in ocular adnexal sebaceous carcinoma
OncoImmunology, 2018 Ocular adnexal sebaceous carcinoma (OASC) is an aggressive malignancy that frequently recurs locally and metastasizes. Surgical extirpation may produce significant aesthetic morbidity, and effective systemic therapies for locally advanced or metastatic ...
Thomas J. Kandl +9 more
doaj +1 more source
Bilateral keratoprostheses in a patient with ocular mucous membrane pemphigoid. [PDF]
, 2019 Mucous membrane pemphigoid (MMP) with ocular involvement, also referred to as ocular cicatricial pemphigoid, is a rare, autoimmune blistering disease that can have devastating effects for patients.
Bromley, Jennifer +2 more
core
Understanding visual map formation through vortex dynamics of spin Hamiltonian models
, 2003 The pattern formation in orientation and ocular dominance columns is one of the most investigated problems in the brain. From a known cortical structure, we build spin-like Hamiltonian models with long-range interactions of the Mexican hat type.
A. Grinvald +16 more
core +1 more source
Microorganisms and Common Ophthalmic Diseases [PDF]
, 2017 The human eye is in constant contact to environmental conditions that increase its likelihood in being exposed to a multitude of pathogens. Studies have revealed that the normal microbial flora found around the ocular area contribute to the well-being of
Su CW, Tighe S
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Frontiers in Immunology, 2018 HSV-1-induced corneal scarring (CS), also broadly referred to as Herpes Stromal Keratitis (HSK), is the leading cause of infectious blindness in developed countries. It is well-established that HSK is in fact an immunopathological disease.
Ujjaldeep Jaggi +5 more
doaj +1 more source