Results 91 to 100 of about 336,794 (287)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Loss of amplitude of accommodation in pre-presbyopic HIV and AIDS patients under treatment with antiretrovirals

open access: yesAfrican Vision and Eye Health, 2017
Background: The prevalence of HIV and AIDS is causing an enormous public health burden. Its manifestations spare no organ. Ocular complications are mainly attributed to various opportunistic infections which are directly or indirectly caused by immune ...
Solani D. Mathebula   +1 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Is Ocular Accommodation Influenced by Dynamic Ambient Illumination and Pupil Size? [PDF]

open access: yesInt J Environ Res Public Health, 2022
Yu H   +6 more
europepmc   +1 more source

Visual discomfort and blur [PDF]

open access: yes, 2013
This work was supported by a doctoral training grant from the BBSRC to LOH.Certain visual stimuli, such as striped patterns and filtered noise, have been reported to be uncomfortable.
Hibbard, Paul Barry   +4 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Association between crystalline lens thickness and intermittent exotropia in children: a cross-sectional observational clinical study

open access: yesEuropean Journal of Medical Research
Purpose To investigate the relationship between crystalline lens thickness (LT) and subtypes of intermittent exotropia (IXT) in children, focusing on ocular biometry and accommodation characteristics.
Jingxin Li   +8 more
doaj   +1 more source

Seeing the future: Predictive control in neural models of ocular accommodation. [PDF]

open access: yesJ Vis, 2022
Read JCA   +5 more
europepmc   +1 more source

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