Results 111 to 120 of about 49,463 (304)

Revolutionizing Eye Care: Exploring the Potential of Microneedle Drug Delivery

Pharmaceutics
Microneedle technology revolutionizes ocular drug delivery by addressing challenges in treating ocular diseases. This review explores its potential impact, recent advancements, and clinical uses.
Satish Rojekar, Swapnali Parit, Amol D. Gholap, Ajit Manchare, Sopan N. Nangare, Navnath Hatvate, Vrashabh V. Sugandhi, Keshav Raj Paudel, Rahul G. Ingle   +8 more
doaj   +1 more source

Immigrants in Health Care: Keeping Americans Healthy Through Care and Innovation [PDF]

, 2016
Immigrants play an outsized and imperative role in the U.S. health care industry. Combining existing data and profiles of immigrants across the health care spectrum, Immigrants in Health Care: Keeping Americans Healthy Through Care and Innovation ...
Marcia D. Hohn
core  

Evidence of suppression of onchocerciasis transmission in the Venezuelan Amazonian focus. [PDF]

, 2016
BACKGROUND: The World Health Organization (WHO) has set goals for onchocerciasis elimination in Latin America by 2015. Most of the six previously endemic countries are attaining this goal by implementing twice a year (and in some foci, quarterly) mass ...
Basanez, MG, Borges, D, Botto, C, Camacho, O, Coronel, P, Cortez, J, Escalona, M, Flores, J, Frontado, H, Graterol, B, Grillet, ME, Guerra, F, Margeli, H, Morales, AL, Noya-Alarcón, O, Rodriguez, MA, Ríos, D, Tovar, Y, Unnasch, TR, Villamizar, NJ, Vivas-Martínez, S   +20 more
core   +2 more sources

ADVANCED NANOCARRIERS FOR OCULAR DRUG DELIVERY: STRATEGIES TO OVERCOME OCULAR BARRIERS

International Journal of Applied Pharmaceutics
Ocular drug delivery is confronted with significant challenges because of the eye's specific anatomy and physiological barriers, including the blood-retinal and corneal epithelium. Traditional dose formulations often experienced rapid precorneal clearance and low absorption. Recent advances in nanotechnology, such as liposomes, cubosomes, glycerosomes,
null DIVYA, RUPA MAZUMDER, ANJNA RANI, RAKHI MISHRA   +3 more
openaire   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

Arthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham, Thea Senger‐Carpenter, Jocelyn Zuckerman, Michelle Adler, Mallet R. Reid, Ashley Danguecan, Luana Flores Pereira, Sarah I. Mossad, Samantha L. Ely, Khalid Abulaban, Elizabeth A. Kessler, Natalie Rosenwasser, Tamar B. Rubinstein, Ekemini A. Ogbu, Emily A. Smitherman, Alaina Miller, Taylor Abounader, Elizabeth Ross, Livie Timmerman, Dhriti Sharma, Jennifer N. Stinson, Stacy Allen, Kabita Nanda, Tala El Tal, Deborah M. Levy, Linda T. Hiraki, Hermine I. Brunner, Mathew Reeves, Steven J. Pierce, Andrea Knight   +29 more
wiley   +1 more source

Research progress of in-situ gelling ophthalmic drug delivery system

Asian Journal of Pharmaceutical Sciences, 2019
Blindness and vision impairment are the most devastating global health problems resulting in a substantial economic and social burden. Delivery of drug to particular parts of the anterior or posterior segment has been a major challenge due to various ...
Yumei Wu, Yuanyuan Liu, Xinyue Li, Dereje Kebebe, Bing Zhang, Jing Ren, Jun Lu, Jiawei Li, Shouying Du, Zhidong Liu   +9 more
doaj   +1 more source

On the barrier properties of the cornea: a microscopy study of the penetration of fluorescently labeled nanoparticles, polymers, and sodium fluorescein [PDF]

, 2014
Overcoming the natural defensive barrier functions of the eye remains one of the greatest challenges of ocular drug delivery. Cornea is a chemical and mechanical barrier preventing the passage of any foreign bodies including drugs into the eye, but the ...
Adrian C. Williams, Amrite A. C., Baba K., Bary A. R., Baydoun L., Bernkop-Schnurch A., Bochot A., Calvo P., Campos A. M., Deutel B., Diebold Y., Eljarrat-Binstock E., Ellina A. Mun, Friedrich I., Geroski D. H., Hao J., Hornof M., Huang A. J. W., Huang H. S., Hughes P. M., Irmukhametova G. S., Irmukhametova G. S., Jarvinen K., Jingjing L., Kaur H., Khutoryanskiy V. V., Lai S. K., Laude A., Loftsson T., Meek K. M., Meek K. M., Morrison P. W. J., Muchtar S., Mun E. A., Newsome D. A., Peter W. J. Morrison, Prydal J. I., Qi H. P., Qu X., Ranta V. P., Reichl S., Sahoo S. K., Saika S., Sharma R., Suh J., Suhonen P., Tegtmeyer S., Thrimawithana T. R., Urtti A., Vitaliy V. Khutoryanskiy, Wilson C. G., Wollensak G., Xu Q., Xu Q., Yorio T.   +54 more
core   +2 more sources

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Ocular drug delivery systems based on nanotechnology: a comprehensive review for the treatment of eye diseases

Discover Nano
Ocular drug delivery is a significant challenge due to the intricate anatomy of the eye and the various physiological barriers. Conventional therapeutic approaches, while effective to some extent, often fall short in effectively targeting ocular diseases,
Rahul Dev Bairagi, Raiyan Rahman Reon, Md Mahbub Hasan, Sumit Sarker, Dipa Debnath, Md. Tawhidur Rahman, Sinthia Rahman, Md. Amirul Islam, Md. Abu Talha Siddique, Bishwajit Bokshi, Md. Mustafizur Rahman, Amit Kumar Acharzo   +11 more
doaj   +1 more source

Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability

Advanced Engineering Materials, EarlyView.
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner, Geo Jacob, Florian Raddatz, Gerko Wende   +3 more
wiley   +1 more source