Results 1 to 10 of about 30,941 (247)
Updates on Biodegradable Formulations for Ocular Drug Delivery [PDF]
Pharmaceutics, 2023 The complex nature of the ocular drug delivery barrier presents a significant challenge to the effective administration of drugs, resulting in poor therapeutic outcomes.
Ta-Hsin Tsung, Yi-Hao Chen, Da-Wen Lu
doaj +4 more sources
Polysaccharides in Ocular Drug Delivery [PDF]
Pharmaceutics, 2019 Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as polysaccharide derivatives, have been successfully used to augment drug delivery in the treatment of ocular pathologies.
Natallia Dubashynskaya +4 more
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Ultrasound-Mediated Ocular Drug Delivery: From Physics and Instrumentation to Future Directions [PDF]
Micromachines, 2023 Drug delivery to the anterior and posterior segments of the eye is impeded by anatomical and physiological barriers. Increasingly, the bioeffects produced by ultrasound are being proven effective for mitigating the impact of these barriers on ocular drug
Blair Duncan +4 more
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Lipid-based nanoparticles: innovations in ocular drug delivery [PDF]
Frontiers in Molecular BiosciencesOcular drug delivery presents significant challenges due to intricate anatomy and the various barriers (corneal, tear, conjunctival, blood-aqueous, blood-retinal, and degradative enzymes) within the eye.
Mirza Salman Baig +12 more
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How to Fabricate Hyaluronic Acid for Ocular Drug Delivery [PDF]
PharmaceuticsThis review aims to examine existing research on the development of ocular drug delivery devices utilizing hyaluronic acid (HA). Renowned for its exceptional biocompatibility, viscoelastic properties, and ability to enhance drug bioavailability, HA is a ...
Martha Kim +5 more
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Penetration Enhancers in Ocular Drug Delivery [PDF]
Pharmaceutics, 2019 There are more than 100 recognized disorders of the eye. This makes the development of advanced ocular formulations an important topic in pharmaceutical science. One of the ways to improve drug delivery to the eye is the use of penetration enhancers. These are defined as compounds capable of enhancing drug permeability across ocular membranes.
Peter Morrison +2 more
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Nanotechnology-based ocular drug delivery systems: recent advances and future prospects [PDF]
Journal of Nanobiotechnology, 2023 Ocular drug delivery has constantly challenged ophthalmologists and drug delivery scientists due to various anatomical and physiological barriers. Static and dynamic ocular barriers prevent the entry of exogenous substances and impede therapeutic agents'
Shiding Li, Liangbo Chen, Yao Fu
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Ocular Drug Delivery: Emerging Approaches and Advances [PDF]
PharmaceuticsComplex anatomical and physiological barriers make the eye a challenging organ to treat from a drug delivery perspective. Currently available treatment methods (topical eyedrops) for anterior segment diseases pose several limitations in terms of ...
Shilpkala Gade +8 more
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Advancements in Nanogels for Enhanced Ocular Drug Delivery: Cutting-Edge Strategies to Overcome Eye Barriers [PDF]
Gels, 2023 Nanomedicine in gel or particle formation holds considerable potential for enhancing passive and active targeting within ocular drug delivery systems.
Hyeonah Lee, Hyeran Noh
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New Challenges in Ocular Drug Delivery. [PDF]
PharmaceuticsThe clinical treatment of diseases affecting the eye globe, and specifically the retina and posterior eye segment, is often hindered by the physiological protection structures and mechanisms of the organ, as well as by the unsuitable physico-chemical features of the active molecules [...]
Pignatello R +3 more
europepmc +5 more sources