Updates on Biodegradable Formulations for Ocular Drug Delivery [PDF]
Pharmaceutics, 2023 The complex nature of the ocular drug delivery barrier presents a significant challenge to the effective administration of drugs, resulting in poor therapeutic outcomes.
Da-Wen Lu, Ta-Hsin Tsung
exaly +4 more sources
Ultrasound-Mediated Ocular Drug Delivery: From Physics and Instrumentation to Future Directions [PDF]
Micromachines, 2023 Drug delivery to the anterior and posterior segments of the eye is impeded by anatomical and physiological barriers. Increasingly, the bioeffects produced by ultrasound are being proven effective for mitigating the impact of these barriers on ocular drug
Blair Duncan +4 more
doaj +2 more sources
Lipid-based nanoparticles: innovations in ocular drug delivery [PDF]
Frontiers in Molecular BiosciencesOcular drug delivery presents significant challenges due to intricate anatomy and the various barriers (corneal, tear, conjunctival, blood-aqueous, blood-retinal, and degradative enzymes) within the eye.
Mirza Salman Baig +12 more
doaj +2 more sources
How to Fabricate Hyaluronic Acid for Ocular Drug Delivery [PDF]
PharmaceuticsThis review aims to examine existing research on the development of ocular drug delivery devices utilizing hyaluronic acid (HA). Renowned for its exceptional biocompatibility, viscoelastic properties, and ability to enhance drug bioavailability, HA is a ...
Martha Kim +5 more
doaj +2 more sources
Nanotechnology-based ocular drug delivery systems: recent advances and future prospects [PDF]
Journal of Nanobiotechnology, 2023 Ocular drug delivery has constantly challenged ophthalmologists and drug delivery scientists due to various anatomical and physiological barriers. Static and dynamic ocular barriers prevent the entry of exogenous substances and impede therapeutic agents'
Shiding Li, Liangbo Chen, Yao Fu
doaj +2 more sources
Ocular Drug Delivery: Emerging Approaches and Advances [PDF]
PharmaceuticsComplex anatomical and physiological barriers make the eye a challenging organ to treat from a drug delivery perspective. Currently available treatment methods (topical eyedrops) for anterior segment diseases pose several limitations in terms of ...
Shilpkala Gade +8 more
doaj +2 more sources
Advancements in Nanogels for Enhanced Ocular Drug Delivery: Cutting-Edge Strategies to Overcome Eye Barriers [PDF]
Gels, 2023 Nanomedicine in gel or particle formation holds considerable potential for enhancing passive and active targeting within ocular drug delivery systems.
Hyeonah Lee, Hyeran Noh
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Vesicular Drug Delivery Systems: Promising Approaches in Ocular Drug Delivery [PDF]
PharmaceuticalsOcular drug delivery poses unique challenges due to the complex anatomical and physiological barriers of the eye. Conventional dosage forms often fail to achieve optimal therapeutic outcomes due to poor bioavailability, short retention time, and off ...
Eslim Batur +3 more
doaj +2 more sources
Topical Ocular Drug Delivery: The Impact of Permeation Enhancers [PDF]
PharmaceuticsTopical ophthalmic drug delivery targeting the posterior segment of the eye has become a key area of interest due to its non-invasive nature, safety, ease of application, patient compliance, and cost-effectiveness.
Gonçalo Santos +4 more
doaj +2 more sources
Ocular drug delivery systems based on nanotechnology: a comprehensive review for the treatment of eye diseases [PDF]
Discover NanoOcular drug delivery is a significant challenge due to the intricate anatomy of the eye and the various physiological barriers. Conventional therapeutic approaches, while effective to some extent, often fall short in effectively targeting ocular diseases,
Rahul Dev Bairagi +11 more
doaj +2 more sources