Results 11 to 20 of about 70,301 (300)
Advancements in Nanogels for Enhanced Ocular Drug Delivery: Cutting-Edge Strategies to Overcome Eye Barriers [PDF]
Gels, 2023 Nanomedicine in gel or particle formation holds considerable potential for enhancing passive and active targeting within ocular drug delivery systems.
Hyeonah Lee, Hyeran Noh
doaj +2 more sources
Topical Ocular Drug Delivery: The Impact of Permeation Enhancers [PDF]
PharmaceuticsTopical ophthalmic drug delivery targeting the posterior segment of the eye has become a key area of interest due to its non-invasive nature, safety, ease of application, patient compliance, and cost-effectiveness.
Gonçalo Santos +4 more
doaj +2 more sources
Ocular drug delivery systems based on nanotechnology: a comprehensive review for the treatment of eye diseases [PDF]
Discover NanoOcular drug delivery is a significant challenge due to the intricate anatomy of the eye and the various physiological barriers. Conventional therapeutic approaches, while effective to some extent, often fall short in effectively targeting ocular diseases,
Rahul Dev Bairagi +11 more
doaj +2 more sources
New Challenges in Ocular Drug Delivery [PDF]
PharmaceuticsThe clinical treatment of diseases affecting the eye globe, and specifically the retina and posterior eye segment, is often hindered by the physiological protection structures and mechanisms of the organ, as well as by the unsuitable physico-chemical features of the active molecules [...]
Pignatello R +3 more
europepmc +4 more sources
Overview of processed excipients in ocular drug delivery: Opportunities so far and bottlenecks [PDF]
HeliyonOcular drug delivery presents a unique set of challenges owing to the complex anatomy and physiology of the eye. Processed excipients have emerged as crucial components in overcoming these challenges and improving the efficacy and safety of ocular drug ...
Sumel Ashique +9 more
doaj +2 more sources
Heliyon, 2023 Soft contact lenses are increasingly being explored as a vehicle for controlled delivery of ophthalmic drugs. However, traditional methods of drug-loading by soaking have limitations such as burst delivery and the release of drugs at the front side of ...
Malake Sarmout +4 more
doaj +1 more source
Pharmaceutics, 2023 Injectable polymer microparticles with the ability to carry and release pharmacologically active agents are attracting more and more interest. This study is focused on the chemical synthesis, characterization, and preliminary exploration of the utility ...
Meitong Shen, Ling Zheng, Leo H. Koole
doaj +1 more source
Scientific Reports, 2021 Small interfering RNA (siRNA) therapy is a promising epigenetic silencing strategy. However, its widespread adoption has been severely impeded by its ineffective delivery into the cellular environment.
Yong Yao Chun +8 more
doaj +1 more source
A Review on Conventional and Novel Topical Ocular Drug Delivery System
Journal of Pharmacy, 2021 Ocular drug delivery is a very challenging area for ophthalmologists and drug delivery scientists due to the structural and barrier complexity of the eye.
Mohamad Faeznudin Rozi +1 more
doaj +1 more source
The AAPS Journal, 2010 Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood-retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution ...
Ripal, Gaudana +3 more
openaire +2 more sources