Results 11 to 20 of about 32,854 (248)
Polysaccharides in Ocular Drug Delivery [PDF]
Pharmaceutics, 2019 Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as polysaccharide derivatives, have been successfully used to augment drug delivery in the treatment of ocular pathologies.
Natallia Dubashynskaya +4 more
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Overview of processed excipients in ocular drug delivery: Opportunities so far and bottlenecks [PDF]
HeliyonOcular drug delivery presents a unique set of challenges owing to the complex anatomy and physiology of the eye. Processed excipients have emerged as crucial components in overcoming these challenges and improving the efficacy and safety of ocular drug ...
Sumel Ashique +9 more
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Overview of Recent Advances in Nano-Based Ocular Drug Delivery [PDF]
International Journal of Molecular Sciences, 2023 Da-Wen Lu
exaly +2 more sources
Heliyon, 2023 Soft contact lenses are increasingly being explored as a vehicle for controlled delivery of ophthalmic drugs. However, traditional methods of drug-loading by soaking have limitations such as burst delivery and the release of drugs at the front side of ...
Malake Sarmout +4 more
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Pharmaceutics, 2023 Injectable polymer microparticles with the ability to carry and release pharmacologically active agents are attracting more and more interest. This study is focused on the chemical synthesis, characterization, and preliminary exploration of the utility ...
Meitong Shen, Ling Zheng, Leo H. Koole
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Scientific Reports, 2021 Small interfering RNA (siRNA) therapy is a promising epigenetic silencing strategy. However, its widespread adoption has been severely impeded by its ineffective delivery into the cellular environment.
Yong Yao Chun +8 more
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A Review on Conventional and Novel Topical Ocular Drug Delivery System
Journal of Pharmacy, 2021 Ocular drug delivery is a very challenging area for ophthalmologists and drug delivery scientists due to the structural and barrier complexity of the eye.
Mohamad Faeznudin Rozi +1 more
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The AAPS Journal, 2010 Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood-retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution ...
Ripal, Gaudana +3 more
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Ocular prodrugs: Attributes and challenges
Asian Journal of Pharmaceutical Sciences, 2021 Ocular drug delivery is one of the most attention-grabbing and challenging endeavors among the numerous existing drug delivery systems. From a drug delivery point of view, eye is an intricate organ to investigate and explore. In spite of many limitations,
Jagpreet kour, Neha Kumari, Bharti Sapra
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MRI in ocular drug delivery [PDF]
NMR in Biomedicine, 2008 AbstractConventional pharmacokinetic methods for studying ocular drug delivery are invasive and cannot be conveniently applied to humans. The advancement of MRI technology has provided new opportunities in ocular drug‐delivery research. MRI provides a means to non‐invasively and continuously monitor ocular drug‐delivery systems with a contrast agent or
S Kevin, Li +2 more
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