Results 21 to 30 of about 70,301 (300)
Ocular prodrugs: Attributes and challenges
Asian Journal of Pharmaceutical Sciences, 2021 Ocular drug delivery is one of the most attention-grabbing and challenging endeavors among the numerous existing drug delivery systems. From a drug delivery point of view, eye is an intricate organ to investigate and explore. In spite of many limitations,
Jagpreet kour, Neha Kumari, Bharti Sapra
doaj +1 more source
MRI in ocular drug delivery [PDF]
NMR in Biomedicine, 2008 AbstractConventional pharmacokinetic methods for studying ocular drug delivery are invasive and cannot be conveniently applied to humans. The advancement of MRI technology has provided new opportunities in ocular drug‐delivery research. MRI provides a means to non‐invasively and continuously monitor ocular drug‐delivery systems with a contrast agent or
S Kevin, Li +2 more
openaire +2 more sources
Disease Models & Mechanisms, 2017 Excessive accumulation of collagen is often used to assess the development of fibrosis. This study aims to identify collagen genes that define fibrosis in the conjunctiva following glaucoma filtration surgery (GFS).
Li-Fong Seet +5 more
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Design of an Implantable Device for Ocular Drug Delivery [PDF]
, 2012 Ocular diseases, such as, glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, and retinitis pigmentosa require drug management in order to prevent blindness and affecting million of adults in USA and worldwide.
Atkinson, Gary M. +3 more
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A Comprehensive Review on Dry Eye Disease: Diagnosis, Medical Management, Recent Developments, and Future Challenges [PDF]
, 2015 Dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS) is a common disorder of the tear film caused by decreased tear production or increased evaporation and manifests with a wide variety of signs and symptoms.
Askarkar, S +4 more
core +2 more sources
Improving Melatonin Delivery Within the Eye [PDF]
, 2017 Melatonin is a neurohormone synthesized in the pineal gland as well as in other organs and it plays an important role in many ocular functions, as it is synthesized in numerous eye structures.
Alkozi, Hanan Awad, Pintor, Jesús
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Pharmaceutics, 2023 Nowadays, ocular drug delivery still remains a challenge, since the conventional dosage forms used for anterior and posterior ocular disease treatments, such as topical, systemic, and intraocular administration methods, present important limitations ...
Letizia Pelusi +6 more
doaj +1 more source
In Vitro Cell Models for Ophthalmic Drug Development Applications [PDF]
, 2016 © Sara Shafaie et al. 2016; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
Ahmed I +46 more
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Dendrimers for ocular drug delivery [PDF]
Canadian Journal of Chemistry, 2017 Existing methods of administering ocular drugs are limited in either their safety or efficiency. Nanomedicine therapies have the potential to address this deficiency by creating vehicles that can control drug biodistribution. Dendrimers are synthetic polymeric nanoparticles with a unique, highly organized branching structure.
Michael G, Lancina, Hu, Yang
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Advances in ophthalmic drug delivery [PDF]
, 2014 Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The
Abdulrazik M +20 more
core +2 more sources