Results 31 to 40 of about 30,941 (247)

Peribulbar poloxamer for ocular drug delivery [PDF]

Acta Ophthalmologica, 2008
Abstract.Purpose:  The use of biopolymers in peribulbar injection for controlled drug delivery provides alternative options to eyedrops and intravitreal or surgical methods. Polymerizable biopolymers are especially likely to have a role because of their particular properties.
Katja, Vehanen, Margit, Hornof, Arto, Urtti, Hannu, Uusitalo   +3 more
openaire   +2 more sources

Ocular Drug Delivery Role of Contact Lenses

Delhi Journal of Ophthalmology, 2015
Significant advances have been made in order to optimize drug delivery to ocular tissues. There has been considerable interest in the potential application of contact lenses for ocular drug delivery.
Anubhav Chauhan
doaj   +1 more source

Caspase-mediated pathways in retinal ganglion cell injury: a novel therapeutic target for glaucoma

Frontiers in Cell and Developmental Biology
Glaucoma is a complex disease of the optic nerve leading to vision loss and blindness, with high worldwide incidence and disproportionate prevalence in older populations.
Nisha Rajakrishna, Nisha Rajakrishna, Seok Ting Lim, Seok Ting Lim, Xiaomeng Wang, Xiaomeng Wang, Xiaomeng Wang, Tina T. Wong, Tina T. Wong, Tina T. Wong   +9 more
doaj   +1 more source

Lipid Nanoparticles as a Promising Drug Delivery Carrier for Topical Ocular Therapy—An Overview on Recent Advances

Pharmaceutics, 2022
Due to complicated anatomical and physical properties, targeted drug delivery to ocular tissues continues to be a key challenge for formulation scientists.
Shery Jacob, Anroop B. Nair, Jigar Shah, Sumeet Gupta, Sai H. S. Boddu, Nagaraja Sreeharsha, Alex Joseph, Pottathil Shinu, Mohamed A. Morsy   +8 more
doaj   +1 more source

Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update

Journal of Nanobiotechnology, 2022
Ocular drug delivery is one of the most challenging endeavors among the various available drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic disease, we have not yet succeeded in achieving a proper drug delivery approach
Mehrdad Afarid, Shirin Mahmoodi, Roghayyeh Baghban   +2 more
doaj   +1 more source

Recent Developments of Nanostructures for the Ocular Delivery of Natural Compounds

Frontiers in Chemistry, 2022
Ocular disorders comprising various diseases of the anterior and posterior segments are considered as the main reasons for blindness. Natural products have been identified as potential treatments for ocular diseases due to their anti-oxidative ...
Malihe Sadat Razavi, Malihe Sadat Razavi, Pedram Ebrahimnejad, Pedram Ebrahimnejad, Yousef Fatahi, Antony D’Emanuele, Rassoul Dinarvand, Rassoul Dinarvand   +7 more
doaj   +1 more source

Nanotechnology approaches for ocular drug delivery

Middle East African Journal of Ophthalmology, 2013
Blindness is a major health concern worldwide that has a powerful impact on afflicted individuals and their families, and is associated with enormous socio-economical consequences. The Middle East is heavily impacted by blindness, and the problem there is augmented by an increasing incidence of diabetes in the population.
Xu, Qingguo, Kambhampati, Siva P., Kannan, Rangaramanujam M.   +2 more
openaire   +3 more sources

Microneedles for advanced ocular drug delivery

Advanced Drug Delivery Reviews, 2023
In the field of ocular drug delivery, topical delivery remains the most common treatment option for managing anterior segment diseases, whileintraocular injectionsare the current gold standard treatment option for treating posterior segment diseases. Nonetheless, topical eye drops are associated with low bioavailability (
Glover, Katie, Mishra, Deepakkumar, Gade, Shilpkala, Vora, Lalitkumar K., Wu, Yu, Paredes, Alejandro J., Donnelly, Ryan F., Singh, Thakur Raghu Raj   +7 more
openaire   +3 more sources

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Emulsion and Emulgel-Based Ophthalmic Drug Delivery Systems

Pharmaceutics
Ophthalmic drug delivery encounters unique challenges due to the anatomical and physiological ocular barriers, necessitating the development of novel drug delivery systems (NDDSs).
Debadatta Mohapatra, Eleen Yang, Timothy W. Corson   +2 more
doaj   +1 more source