Results 31 to 40 of about 32,854 (248)
Ocular Drug Delivery Role of Contact Lenses
Delhi Journal of Ophthalmology, 2015 Significant advances have been made in order to optimize drug delivery to ocular tissues. There has been considerable interest in the potential application of contact lenses for ocular drug delivery.
Anubhav Chauhan
doaj +1 more source
Nanoliposomal minocycline for ocular drug delivery [PDF]
Nanomedicine: Nanotechnology, Biology and Medicine, 2013 Nanoliposomal technology is a promising drug delivery system that could be employed to improve the pharmacokinetic properties of clearance and distribution in ocular drug delivery to the retina. We developed a nanoscale version of an anionic, cholesterol-fusing liposome that can encapsulate therapeutic levels of minocycline capable of drug delivery. We
James M, Kaiser +12 more
openaire +2 more sources
Advances in ocular drug delivery systems [PDF]
Eye, 2020 Recent advances in pharmacological agents have led to successful treatment of a variety of retinal diseases such as neovascular age-related macular degeneration (AMD), diabetic macular oedema (DMO), and retinal vascular occlusions (RVO). These treatments often require repeated drug injections for an extended period of time.
Jennifer J, Kang-Mieler +3 more
openaire +2 more sources
Journal of Nanobiotechnology, 2022 Ocular drug delivery is one of the most challenging endeavors among the various available drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic disease, we have not yet succeeded in achieving a proper drug delivery approach
Mehrdad Afarid +2 more
doaj +1 more source
Recent Developments of Nanostructures for the Ocular Delivery of Natural Compounds
Frontiers in Chemistry, 2022 Ocular disorders comprising various diseases of the anterior and posterior segments are considered as the main reasons for blindness. Natural products have been identified as potential treatments for ocular diseases due to their anti-oxidative ...
Malihe Sadat Razavi +7 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Nanotechnology approaches for ocular drug delivery
Middle East African Journal of Ophthalmology, 2013 Blindness is a major health concern worldwide that has a powerful impact on afflicted individuals and their families, and is associated with enormous socio-economical consequences. The Middle East is heavily impacted by blindness, and the problem there is augmented by an increasing incidence of diabetes in the population.
Xu, Qingguo +2 more
openaire +3 more sources
Emulsion and Emulgel-Based Ophthalmic Drug Delivery Systems
PharmaceuticsOphthalmic drug delivery encounters unique challenges due to the anatomical and physiological ocular barriers, necessitating the development of novel drug delivery systems (NDDSs).
Debadatta Mohapatra +2 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Ophthalmic Drug Delivery Systems for Antibiotherapy—A Review
Pharmaceutics, 2018 The last fifty years, ophthalmic drug delivery research has made much progress, challenging scientists about the advantages and limitations of this drug delivery approach.
Marion Dubald +3 more
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