Intravitreal injection of Ozurdex(®) implant in patients with persistent diabetic macular edema, with six-month follow-up [PDF]
, 2016 AIM: To evaluate the efficacy of intravitreal dexamethasone injections in diabetic macular edema (DME). METHODS: A 700 μg slow-release intravitreal dexamethasone implant (Ozurdex®) was placed in the vitreal cavity of 17 patients (19 eyes) affected ...
Bottone, A +8 more
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Insights to Using Contact Lenses for Drug Delivery [PDF]
, 2013 Phan, C.-M. (2013). Insights to Using Contact Lenses for Drug Delivery. Clinical & Experimental Pharmacology, 04(01). https://doi.org/10.4172/2161-1459.1000145There has been considerable interest in the potential application of contact lenses for ocular ...
Gao, Huayi +5 more
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Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level. [PDF]
, 2018 ‘A picture is worth a thousand words’ is an idiom from the English language (‘borrowed’ from on old Chinese proverb) that conveys the notion that a complex idea can be succinctly and fully described by a single image. Never has this expression been truer
Andrén, PE +11 more
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Ocular Drug Delivery Role of Contact Lenses
Delhi Journal of Ophthalmology, 2015 Significant advances have been made in order to optimize drug delivery to ocular tissues. There has been considerable interest in the potential application of contact lenses for ocular drug delivery.
Anubhav Chauhan
doaj +1 more source
Caspase-mediated pathways in retinal ganglion cell injury: a novel therapeutic target for glaucoma
Frontiers in Cell and Developmental BiologyGlaucoma is a complex disease of the optic nerve leading to vision loss and blindness, with high worldwide incidence and disproportionate prevalence in older populations.
Nisha Rajakrishna +9 more
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Pharmaceutics, 2022 Due to complicated anatomical and physical properties, targeted drug delivery to ocular tissues continues to be a key challenge for formulation scientists.
Shery Jacob +8 more
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Journal of Nanobiotechnology, 2022 Ocular drug delivery is one of the most challenging endeavors among the various available drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic disease, we have not yet succeeded in achieving a proper drug delivery approach
Mehrdad Afarid +2 more
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Recent Developments of Nanostructures for the Ocular Delivery of Natural Compounds
Frontiers in Chemistry, 2022 Ocular disorders comprising various diseases of the anterior and posterior segments are considered as the main reasons for blindness. Natural products have been identified as potential treatments for ocular diseases due to their anti-oxidative ...
Malihe Sadat Razavi +7 more
doaj +1 more source
Pro-Secretory Activity and Pharmacology in Rabbits of an Aminophenyl-1,3,5-Triazine CFTR Activator for Dry Eye Disorders. [PDF]
, 2017 PurposePharmacological activation of ocular surface cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels is a potential pro-secretory approach to treat dry eye disorders.
Felix, Christian M +3 more
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Latanoprost with high precision, piezo-print microdose delivery for IOP lowering: clinical results of the PG21 study of 0.4 µg daily microdose. [PDF]
, 2018 Background:Topical high-precision piezo-print delivery of microdoses of latanoprost achieved significant IOP reduction consistent with the eyedropper effect but with a 75% reduced exposure to drugs and preservatives.
Ianchulev, Tsontcho +5 more
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