Results 1 to 10 of about 5,246,989 (312)

Possible Strategies to Mitigate Placebo or Vehicle Response in Dry Eye Disease Trials: A Narrative Review

open access: yesOphthalmology and Therapy, 2023
Many candidate drugs for dry eye disease (DED) have been assessed over the years in pursuit of demonstrating efficacy in both signs and symptoms. However, patients with DED have very limited treatment options for management of both signs and symptoms of ...
Michela Montecchi-Palmer   +5 more
doaj   +1 more source

Orbitofrontal cholesterol granuloma masquerading as frontal sinus mucoceles: report of two cases

open access: yesBMC Ophthalmology, 2023
Background Two cases of orbitofrontal cholesterol granuloma masquerading as frontal sinus mucoceles were reported to understand image findings, clinical and histopathologic features of orbitofrontal cholesterol granuloma to improve its diagnosis and ...
Ruimiao Li   +5 more
doaj   +1 more source

Analysis on short-term change of macular function and the correlates after intravitreal conbercept for CRVO-ME

open access: yesBMC Ophthalmology, 2022
Aim To study the short-term change of macular function and the correlates after intravitreal conbercept for CRVO-ME. Study design Prospective, clinical study.
Yun-Chang Wang   +4 more
doaj   +1 more source

Topical fosaprepitant for the treatment of ocular pain and inflammation

open access: yesAmerican Journal of Ophthalmology Case Reports, 2023
Purpose: To assess whether topical administration of fosaprepitant improves intractable chronic ocular pain and inflammation. Methods: We report three clinical cases of female patients with drug-resistant ocular pain associated with inflammatory diseases
Giuseppe Suanno   +4 more
doaj   +1 more source

Functional connectivity density alterations in children with strabismus and amblyopia based on resting-state functional magnetic resonance imaging (fMRI)

open access: yesBMC Ophthalmology, 2022
Purpose To explore functional connectivity density (FCD) values of brain areas in children with strabismus and amblyopia (SA) based on blood oxygen level-dependent (BOLD) signals. Methods This study recruited 26 children (14 male, 12 females) with SA and
Yi-Dan Shi   +7 more
doaj   +1 more source

Visualization of deep choroidal vasculatures and measurement of choroidal vascular density: a swept-source optical coherence tomography angiography approach

open access: yesBMC Ophthalmology, 2020
Background To investigate swept-source optical coherence tomography angiography (SS-OCTA) for deep choroid visualization and choroidal vascular density (CVD) measurement.
Erqian Wang   +3 more
doaj   +1 more source

Altered brain network centrality in middle‐aged patients with retinitis pigmentosa: A resting‐state functional magnetic resonance imaging study

open access: yesBrain and Behavior, 2021
Objective The purpose of this study is to explore the underlying functional network brain activity changes of patients in middle‐aged with retinitis pigmentosa (RP) and the relationships with clinical features such as depression scale and visual ...
Qi Lin   +9 more
doaj   +1 more source

Multimodal therapy in the management of primary orbital mesenchymal chondrosarcoma [PDF]

open access: yesInternational Journal of Ophthalmology, 2022
AIM: To evaluate the ophthalmic manifestations, radiographic features, and prognosis of Chinese patients with primary orbital mesenchymal chondrosarcoma (MCS).
Yun Zhao   +4 more
doaj   +1 more source

Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To explore the effect of parthenolide (PTL) on human uveal melanoma (UM) cells (C918 and SP6.5 cells) and its molecular mechanism. METHODS: Carboxyfluorescein succinimidyl amino ester (CFSE) assays and cell counting kit-8 (CCK-8) were performed to ...
Song-Tian Che   +5 more
doaj   +1 more source

AFP and CA-125 as an accurate risk factor to predict eye metastasis in hypertension patients with liver carcinoma: A STROBE-compliant article

open access: yesFrontiers in Genetics, 2022
Purpose: In this study, we analyzed the differences between hypertension patients with ocular metastasis of liver cancer and those with metastases to other sites, the correlation between history of HBV and liver cancer metastasis, and independent risk ...
Jing Tang   +9 more
doaj   +1 more source

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