Results 251 to 260 of about 49,463 (304)
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Association between periodontitis and blood-ocular barrier disruption
European Journal of Ophthalmology, 2022PurposePeriodontitis causes low-grade systemic inflammation e.g., through circulatory periodontal endotoxins, and it has been associated with cardiovascular morbidity and wet age-related macular degeneration.MethodsTo assess the association between clinical severity of periodontitis and aqueous flare levels in the eyes. Patients with periodontitis (N =
Karesvuo Petteri +7 more
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Radionuclide study of the blood ocular barrier
European Journal of Drug Metabolism and Pharmacokinetics, 1985The purpose of this study was to investigate the permeability and clinical significance of the blood-ocular barrier. A new technique using systemic, subtenon, and retrobulbar injections was applied to the study of intraocular penetration of labelled steroid compound.
G, Ziada +5 more
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Cell culture models of the ocular barriers
European Journal of Pharmaceutics and Biopharmaceutics, 2005The presence of tight barriers, which regulate the environment of ocular tissues in the anterior and posterior part of the eye, is essential for normal visual function. The development of strategies to overcome these barriers for the targeted ocular delivery of drugs, e.g. to the retina, remains a major challenge.
Margit, Hornof +2 more
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Survey of Ophthalmology, 1979
The introduction of the concept of blood-ocular barriers in the ophthalmic literature is briefly reviewed. Two main blood-ocular barriers are proposed: the blood-aqueous barrier and the blood-retinal barrier. The blood-aqueous barrier is formed by an epithelial barrier located in the nonpigmented layer of the ciliary epithelium and in the posterior ...
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The introduction of the concept of blood-ocular barriers in the ophthalmic literature is briefly reviewed. Two main blood-ocular barriers are proposed: the blood-aqueous barrier and the blood-retinal barrier. The blood-aqueous barrier is formed by an epithelial barrier located in the nonpigmented layer of the ciliary epithelium and in the posterior ...
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1989
No treatise on the blood-brain barrier (BBB) is complete without a discussion of the barriers between the blood and the most specialized portion of the central nervous system (CNS), the eye. The eye is a complex organ with distinct anatomic structures and blood supplies that form several nonuniform blood–ocular barriers (Fig. 1).
Mark J. Kupersmith, Manoucher Shakib
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No treatise on the blood-brain barrier (BBB) is complete without a discussion of the barriers between the blood and the most specialized portion of the central nervous system (CNS), the eye. The eye is a complex organ with distinct anatomic structures and blood supplies that form several nonuniform blood–ocular barriers (Fig. 1).
Mark J. Kupersmith, Manoucher Shakib
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Neurology, 2018
Acute stroke has a major effect on the cerebral vasculature with disruption of the neurovascular unit, leading to vasogenic edema. Breakdown of the blood-brain barrier (BBB) in ischemic stroke occurs in the early phases of ischemia, and is accentuated by IV treatment with recombinant tissue plasminogen activator, which increases the risk of hemorrhagic
Felix, Schlachetzki, Gary A, Rosenberg
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Acute stroke has a major effect on the cerebral vasculature with disruption of the neurovascular unit, leading to vasogenic edema. Breakdown of the blood-brain barrier (BBB) in ischemic stroke occurs in the early phases of ischemia, and is accentuated by IV treatment with recombinant tissue plasminogen activator, which increases the risk of hemorrhagic
Felix, Schlachetzki, Gary A, Rosenberg
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Barrier Function of Ocular Surface Epithelium
1997This paper demonstrates three different types of corneal epithelial barrier dysfunction: mechanically and/or immunologically oriented (as in superficial punctate kera- topathy); genetically regulated (as in corneal dystrophy); and biologically based (as in conjunctival epithelial invasion of the cornea). Corneal epithelial barrier function was examined
Shigeru Kinoshita +2 more
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Blood‐Ocular Barriers and Macular Edema
Acta Ophthalmologica, 2011AbstractThe blood‐ocular barrier system is formed by two main barriers: the blood‐aqueous barrier (BAB) and the blood‐retinal barrier (BRB). Homeostasis in the retina microenvironment is maintained by the function of the BRB which regulates the movement of chemicals and cells between the intravascular compartment and the retina. The BRB consists of two
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