Results 151 to 160 of about 172,858 (187)
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Immunosuppressive Therapy in Ocular Cicatricial Pemphigoid
American Journal of Ophthalmology, 1983To evaluate the efficacy of systemic immunosuppressive drugs, including corticosteroids, in the long-term treatment of ocular cicatricial pemphigoid, we conducted a prospective clinical trial in 57 patients (34 women and 23 men ranging in age from 46 to 94 years). Each patient was assigned to one of five groups.
B J, Mondino, S I, Brown
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Atopy in Patients With Ocular Cicatricial Pemphigoid
Cornea, 2018Purpose: To evaluate the presence of atopy in patients with ocular cicatricial pemphigoid (OCP). Method: Patient encounters between August 2005 and November 2016 at the Massachusetts Eye Research and Surgery Institute (MERSI) were searched to identify those with biopsy-proven OCP ...
Nazanin, Ebrahimiadib +4 more
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Systemic Chemotherapy for Ocular Cicatricial Pemphigoid
Cornea, 1991The records of 105 patients treated with three different chemotherapeutic agents for ocular cicatricial pemphigoid (OCP) were reviewed to compare long-term efficacies, side effects, and tolerance of different regimens. For the entire group, OCP progressed in 6% of eyes in 10% of patients (follow-up 35 months).
J, Tauber +2 more
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Autoimmune Phenomena in Ocular Cicatricial Pemphigoid
American Journal of Ophthalmology, 1977Twelve patients with various stages of ocular cicatricial pemphigoid were studied. Tear volumes measured by Schirmer tests and visual acuities were generally reduced in proportion to disease severity. Mannitol-positive staphylococcus was recovered from 67% (16/24) of the eyelids cultured.
B J, Mondino +3 more
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Immunofluorescent Studies of Ocular Cicatricial Pemphigoid
American Journal of Ophthalmology, 1975Using direct and indirect immunofluorescent techniques, we studied ten patients with cicatricial pemphigoid (chronic cicatricial conjunctivitis). Serologic and histologic evaluation of 13 conjunctival, 12 mucous membrane, and 11 skin specimens from the ten patients showed that three had immunoglobulin deposition at the basement membrane zone of the ...
N, Furey +4 more
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2005
Ocular cicatricial pemphigoid is a result of immune dysfunction leading to deposition of immunoglobulins and complement at the conjunctival basement membrane zone. This can lead to irreversible scarring. Patients are treated with suitable systemic immunomodulatory treatments which are usually individualized to the patient depending on the patient’s age,
Ahmed Muna, C. Stephen Foster
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Ocular cicatricial pemphigoid is a result of immune dysfunction leading to deposition of immunoglobulins and complement at the conjunctival basement membrane zone. This can lead to irreversible scarring. Patients are treated with suitable systemic immunomodulatory treatments which are usually individualized to the patient depending on the patient’s age,
Ahmed Muna, C. Stephen Foster
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Cataract Surgery in Ocular Cicatricial Pemphigoid
Ophthalmology, 1988The authors report the results of their experience with cataract surgery in 20 patients (26 eyes) with biopsy-proven cicatricial pemphigoid. All patients were on systemic immunosuppression at the time of surgery (dapsone, azathioprine, cyclophosphamide, or combinations) and were treated with perioperative oral corticosteroids.
M, Sainz de la Maza +2 more
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Ocular cicatricial pemphigoid: Manifestations and management
Current Allergy and Asthma Reports, 2005Ocular cicatricial pemphigoid (OCP) is a chronic, progressive cicatrizing inflammatory disease of presumed autoimmune etiology affecting the mucous membranes and skin. It has sight-threatening ocular manifestations and potentially life-threatening extraocular manifestations.
John H, Chang, Peter J, McCluskey
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Immunofluorescent studies in ocular cicatricial pemphigoid
British Journal of Dermatology, 1988Twenty nine patients with cicatrizing conjunctivitis were studied; 17 with a clinical diagnosis of cicatricial pemphigoid, five with a clinical diagnosis of pseudopemphigoid caused by long-term application of topical medication and seven who had a cicatrizing conjunctivitis from other causes.
J N, Leonard +6 more
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Glaucoma in Patients with Ocular Cicatricial Pemphigoid
Ophthalmology, 1989This retrospective review of 111 patients with ocular cicatricial pemphigoid (CP) identifies 29 patients (26%) with glaucoma. Twenty-seven of these patients had a history of glaucoma for a mean of 11.3 years before the diagnosis of CP was made. Most had advanced glaucoma, with a long history of medication use, optic nerve damage, and visual field loss.
J, Tauber, S, Melamed, C S, Foster
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