Results 101 to 110 of about 5,246,989 (312)

Evaluating neutrophil-lymphocyte ratio, systemic immune-inflammation index, and systemic inflammation response index for diagnosing and predicting progression in diabetic retinopathy: a cross-sectional and longitudinal study

BMC Ophthalmology
Purpose To investigate the significance of neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI), as diagnostic and prognostic factors in patients with diabetic retinopathy (DR) in
Yi Gong, Linni Wang, Qingbo Li, Manqiao Wang, Rong Luan, Fei Gao, Liying Hu, Chen Chen, Juping Liu, Yan Shao, Xiaorong Li   +10 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Clinical Use Of Non-Steroidal Anti-Inflammatory Drugs In Ocular Diseases

, 2019
This thesis covers a range of ocular disease in which the use of NSAIDs is evaluated. The mechanism of how NSAIDs function and there advantages and disadvantages within the speciality of ophthalmology.
Pindoria, Bhavesh
core  

Palladium-103 plaque radiation therapy for retinal angioma

American Journal of Ophthalmology Case Reports
Purpose: Plaque radiation has been used in the treatment of angiomas of the choroid, retina, and vasoproliferative tumors of the retina. Herein, is presented the novel use of palladium-103 (103Pd) plaque radiation as primary treatment for retinal angioma.
Paul T. Finger, Andrew Lukban, Ren-Dih Sheu, Robert D. Stewart, Julie R. Bloom, Kenneth E. Rosenzweig   +5 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Diagnóstico de tuberculose ocular

, 2016
A tuberculose ocular continua sendo um diagnóstico clínico presuntivo, pois os testes padrão-ouro para diagnosticar a tuberculose ocular geralmente não são úteis: as culturas de Mycobacterium tuberculosis requerem semanas para serem processadas em meio ...
Marcus Ang, Massimo Accorinti, Daniel Vítor de Vasconcelos Santos, Amod Gupta, Aman Sharma, Soon-Phaik Chee, Kusum Sharma, Narsing Rao   +7 more
core   +1 more source

The Significance of Ocular Findings in the Diagnosis of Fabry’s Disease [PDF]

, 2011
Fabry’s disease is an X-linked, inherited disorder caused by a deficiency of the enzyme alfa-galactosidase A and characterized by progressive accumulation of glycosphingolipids within several tissues and organs, including the eye.
Fazıl Cüneyt Erdurman, Cem Özgönül, Osman Melih Ceylan, Üzeyir Erdem, Volkan Hürmeriç   +4 more
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Ocular surface disease in patients with glaucoma or ocular hypertension treated with either BAK-preserved latanoprost or BAK-free travoprost

, 2010
Gregory Katz1, Clark L Springs2, E Randy Craven3, Michela Montecchi-Palmer41Huron Ophthalmology, Ypsilanti, MI, USA; 2Indiana University Eye Care, Indianapolis, IN, USA; 3Specialty Eye Care, Denver, CO, USA; 4Alcon Research Ltd., Fort Worth, TX ...
Clark L Springs, et al, Gregory Katz, E Randy Craven   +3 more
core  

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source