Results 71 to 80 of about 5,246,989 (312)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Systemic and Bilateral Severe Ocular Toxoplasmosis Resembling Autoimmune Phenomena: A Case Report

open access: yes
Purpose: To present an atypical case of severe bilateral ocular toxoplasmosis with systemic involvement that initially mimicked an autoimmune etiology, posing challenges to its diagnosis and treatment.
Muñoz-Ortiz J.   +5 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Behcet's disease in Western Switzerland: epidemiology and analysis of ocular involvement

open access: yes, 2002
PURPOSE: To determine the epidemiology of Behcet's disease in Western Switzerland and to study the characteristics of ocular disease. METHODS: Patients newly diagnosed with Behcet's disease, seen from January 1990 to December 1998 at Hopital Jules Gonin,
Ambresin, A.   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Ocular disorders in children with learning disabilities in special education schools of Pune, India. [PDF]

open access: yes, 2011
AIM: The aim was to study and treat ocular disorders in children with learning disabilities (cLDs) and explore associations with their perinatal history.
Gilbert, Clare   +12 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Ocular surface disease in posttrabeculectomy/mitomycin C patients

open access: yes, 2015
Janice Lam,1,2 Tina T Wong,1–4 Louis Tong1–3,5 1Singapore National Eye Centre, Singapore; 2Singapore Eye Research Institute, Singapore; 3Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore ...
Wong, Tina Tzeeling   +5 more
core   +1 more source

Two-stage diagnostic intervals in diabetic retinopathy and associated factors: a cross-sectional study

open access: yesBMC Ophthalmology
Objective To characterize two stage-specific diagnostic intervals in diabetic retinopathy (DR) and examine factors associated with each stage. Methods In this cross-sectional study, 283 patients newly diagnosed with DR were enrolled.
Manling Lin   +6 more
doaj   +1 more source

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