Results 41 to 50 of about 1,894 (248)

Coordinated optimization of visual cortical maps : 1. Symmetry-based analysis

, 2012
In the primary visual cortex of primates and carnivores, functional architecture can be characterized by maps of various stimulus features such as orientation preference (OP), ocular dominance (OD), and spatial frequency.
Heide, Dominik, Justin C. Crowley (120185), Wolf, Fred, Dominik Heide, Fred Wolf, Matthias Kaschube, Heide, D., Löwel, Siegrid, Crowley, Justin C., Kaschube, Matthias, Dominik Heide (120181), Reichl, L., Kaschube, M., Justin C Crowley, Reichl, Lars, Löwel, S., Lars Reichl, Lars Reichl (120178), Siegrid Löwel, Wolf, F., Siegrid Löwel (53603), Fred Wolf (120189), Crowley, J., Matthias Kaschube (120187)   +23 more
core   +1 more source

Internal neural states influence the short-term effect of monocular deprivation in human adults

eLife, 2023
The adult human visual system maintains the ability to be altered by sensory deprivation. What has not been considered is whether the internal neural states modulate visual sensitivity to short-term monocular deprivation. In this study we manipulated the
Yiya Chen, Yige Gao, Zhifen He, Zhouyuan Sun, Yu Mao, Robert F Hess, Peng Zhang, Jiawei Zhou   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Coordinated optimization of visual cortical maps : 2. Numerical studies

, 2012
In the juvenile brain, the synaptic architecture of the visual cortex remains in a state of flux for months after the natural onset of vision and the initial emergence of feature selectivity in visual cortical neurons. It is an attractive hypothesis that
Heide, Dominik, Justin C. Crowley (120185), Wolf, Fred, Dominik Heide, Fred Wolf, Matthias Kaschube, Löwel, Siegrid, Crowley, Justin C., Kaschube, Matthias, Dominik Heide (120181), Justin C Crowley, Reichl, Lars, Lars Reichl, Lars Reichl (120178), Siegrid Löwel, Siegrid Löwel (53603), Fred Wolf (120189), Matthias Kaschube (120187)   +17 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Association between central corneal thickness and ocular dominance in a South Indian population

TNOA Journal of Ophthalmic Science and Research, 2021
Aims: The aim of the study is to investigate the association between ocular dominance and central corneal thickness (CCT) among normal eyes. Settings and Design: A cross-sectional study was conducted in the outpatient department of a tertiary care center
Prasanna Venkatesh Ramesh, Sathyan Parthasarathi, Rajesh Kumar John   +2 more
doaj   +1 more source

The difference in accommodative amplitude and facility between the dominant and non-dominant eyes

Journal of the Pakistan Medical Association
The cross-sectional study was planned to compare the amplitude of accommodation and accommodative facility between the dominant and non-dominant eyes in young university students.
Basal Hamad Altoaimi
doaj   +1 more source

Dark Rearing Promotes the Recovery of Visual Cortical Responses but Not the Morphology of Geniculocortical Axons in Amblyopic Cat

Frontiers in Neural Circuits, 2021
Monocular deprivation (MD) of vision during early postnatal life induces amblyopia, and most neurons in the primary visual cortex lose their responses to the closed eye. Anatomically, the somata of neurons in the closed-eye recipient layer of the lateral
Takahiro Gotou, Katsuro Kameyama, Katsuro Kameyama, Ayane Kobayashi, Kayoko Okamura, Takahiko Ando, Keiko Terata, Chihiro Yamada, Hiroyuki Ohta, Ayaka Morizane, Yoshio Hata, Yoshio Hata   +11 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Best of Both Worlds: Adaptation During Natural Tasks Produces Long-Lasting Plasticity in Perceptual Ocular Dominance

, 2017
In human vision, one eye is usually stronger than the other. This is called ocular dominance. Extremely imbalanced ocular dominance can be found among certain patient groups, for example, in patients with amblyopia.
Bao, Min, Liu, Lijuan, Engel, Stephen A., Lijuan Liu, Min Bao, Jiang, Yi, Dong, Bo, Yi Jiang, Bo Dong, Stephen A. Engel   +9 more
core   +1 more source