Results 241 to 250 of about 1,264,680 (377)

Ocular Hypertension Treatment Study [PDF]

Archives of Ophthalmology, 2009
openaire   +2 more sources

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source

Visual field progression patterns in the ocular hypertension treatment study correspond to vulnerability regions of the disc

Ari Leshno, Nikhil Bommakanti, Carlos Gustavo De Moraes, Mae O. Gordon, Michael A. Kass, George A. Cioffi, Jeffrey M. Liebmann   +6 more
openalex   +2 more sources

Ten-Year Effectiveness and Safety of Trabecular Micro-Bypass Stent Implantation with Cataract Surgery in Patients with Glaucoma or Ocular Hypertension [PDF]

T Neuhann, Raphael Neuhann, Dana M. Hornbeak   +2 more
openalex   +1 more source

Short-term ocular tolerability of dorzolamide 2% and brinzolamide 1% vs placebo in primary open-angle glaucoma and ocular hypertension subjects [PDF]

, 2004
William C. Stewart, Douglas G. Day, Jeanette A. Stewart, Keri T Holmes, Jessica N. Jenkins   +4 more
openalex   +1 more source

Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS

Drug Testing and Analysis, EarlyView.
Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner, Hannah Rämisch, Laura Besch, Johannes Schmeinck, Uwe Karst   +4 more
wiley   +1 more source

Gene therapy for ocular hypertension using hfCas13d-mediated mRNA targeting. [PDF]

PNAS Nexus
Chen S, Liu Z, Lo CH, Wang Q, Ning K, Zhang Q, Zhao J, Shen Y, Sun Y.   +8 more
europepmc   +1 more source

Oxytocin Effects on Food Stimulus Processing and Food Intake in Females With or Without Binge Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating disorder (BED) is maintained by increased food‐related incentive salience, which is reflected by an attentional bias for food. Oxytocin acutely attenuates this bias in patients with anorexia nervosa and reduces food intake in males with normal or increased body weight.
Julia Nannt, Mechteld M. van den Hoek Ostende, Brunna Tuschen‐Caffier, Markus Heinrichs, Daniel Sippel, Manfred Hallschmid, Jennifer Svaldi   +6 more
wiley   +1 more source

TRPV4 activation by TGFβ2 enhances cellular contractility and drives ocular hypertension. [PDF]

Elife
Rudzitis CN, Lakk M, Singh A, Redmon SN, Kirdajová D, Tseng YT, De Ieso ML, Stamer WD, Herberg S, Krizaj D.   +9 more
europepmc   +1 more source

Rho Kinase Inhibitors as a Novel Treatment for Glaucoma and Ocular Hypertension.

Ophthalmology (Rochester, Minn.), 2018
A. Tanna, Mark Johnson
semanticscholar   +1 more source