Results 61 to 70 of about 1,191,327 (361)

Mouse model of ocular hypertension with retinal ganglion cell degeneration

PLoS ONE, 2019
Objectives Ocular hypertension is a primary risk factor for glaucoma and results in retinal ganglion cell (RGC) degeneration. Current animal models of glaucoma lack severe RGC cell death as seen in glaucoma, making assessment of physiological mediators ...
Ryo Mukai, D. Park, Y. Okunuki, Eiichi Hasegawa, Garrett Klokman, Clifford B. Kim, A. Krishnan, M. Gregory-Ksander, D. Husain, Joan W. Miller, K. Connor   +10 more
semanticscholar   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source

Latanoprostene Bunod Ophthalmic Solution 0.024%: A Review in Open-Angle Glaucoma and Ocular Hypertension

Drugs, 2018
Latanoprostene bunod ophthalmic solution 0.024% (hereafter referred to as latanoprostene bunod 0.024%) [Vyzulta™] is a nitric oxide (NO)-donating prostaglandin F2α analogue approved in the USA for the reduction of intraocular pressure (IOP) in patients ...
Sheridan M. Hoy
semanticscholar   +1 more source

Detachable and Reusable: Reinforced π‐Ion Film for Modular Synaptic Reservoir Computing

Advanced Materials, EarlyView.
This study presents a reinforced π‐ion film for organic electrochemical transistors (OECTs), addressing the rapid degradation of organic semiconductor layers. By introducing a mesh support and utilizing a scalable solvent exchange method, the π‐ion film enhances detachability and stability.
Gyu Won Woo, Chang Min Lee, Won Woo Lee, Min Ju Jung, Seung Min Lee, Hye Won Lee, Hocheon Yoo, Yong Hee Kim, Eun Kwang Lee   +8 more
wiley   +1 more source

Incidence and outcomes of ocular hypertension from rhegmatogenous retinal detachment surgery in the acute postoperative setting

Clinical Ophthalmology, 2019
Albert John Bromeo, Nilo Vincent FlorCruzDepartment of Ophthalmology and Visual Sciences, Philippine General Hospital, University of the Philippines Manila, Manila, PhilippinesCorrespondence: Albert John BromeoSentro Oftalmologico Jose Rizal, Philippine ...
Bromeo AJ, FlorCruz NV
doaj  

Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension

Investigative Ophthalmology and Visual Science, 2019
Purpose Reoxygenation after hypoxia can increase reactive oxygen species and upregulate autophagy. We determined, for the first time, the impact of elevated IOP on hypoxia induction, superoxide accumulation, and autophagy in a bead model of glaucoma ...
A. H. Jassim, D. Inman
semanticscholar   +1 more source

Structure and Electrochemical Properties of ReS2‐LaFeO3 Nanocomposite for Dopamine Sensing

Advanced Sensor Research, EarlyView.
A novel ReS2‐LaFeO3 nanocomposite is developed for sensitive and reliable detection of dopamine (DA), an important neurotransmitter. The material performs well even in complex biological samples, demonstrating strong selectivity and accuracy. These findings highlight its potential for future applications in medical diagnostics and neuroscience research.
Obed Graham Keelson, Rajeev Kumar, Amit Kumar Shringi, Hazel Achieng Ouma, Pooja D. Walimbe, Fei Yan   +5 more
wiley   +1 more source

Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma

Cell Death and Disease, 2022
Ocular hypertension is a significant risk factor for vision loss in glaucoma due to the death of retinal ganglion cells (RGCs). This study investigated the effects of the antiapoptotic peptides peptain-1 and peptain-3a on RGC death in vitro in rat ...
Mi-Hyun Nam, Dorota L. Stankowska, Gretchen A. Johnson, Rooban B. Nahomi, Mina B. Pantcheva, Ram H. Nagaraj   +5 more
doaj   +1 more source

Latanoprostene bunod ophthalmic solution 0.024%: a new treatment option for open‐angle glaucoma and ocular hypertension

Clinical and experimental optometry, 2019
Latanoprostene bunod (LBN) ophthalmic solution 0.024% is a novel, once‐daily, nitric oxide‐donating prostaglandin analogue for the lowering of intraocular pressure (IOP) in patients with open‐angle glaucoma and ocular hypertension.
M. Fingeret, I. Gaddie, M. Bloomenstein
semanticscholar   +1 more source