Results 61 to 70 of about 106,911 (284)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Association of severity of primary open-angle glaucoma with serum vitamin D levels in patients of African descent. [PDF]

, 2019
PurposeTo study the relationship between primary open-angle glaucoma (POAG) in a cohort of patients of African descent (AD) and serum vitamin D levels.MethodsA subset of the AD and glaucoma evaluation study III (ADAGES III) cohort, consisting of 357 ...
ADAGES III Genomics Study Group, Arzumanyan, Zorayr, Ayyagari, Radha, Chen, Yii-der I, Dirkes, Keri, Dubiner, Harvey, Feldman, Robert, Girkin, Christopher A, Guo, Xiuqing, Hai, Yang, Hammel, Naama, Holman, Matt, Liebmann, Jeffrey M, Rotter, Jerome I, Slight, Rigby, Taylor, Kent D, Weinreb, Robert N, Zangwill, Linda M   +17 more
core  

A Novel Reporter Mouse Uncovers Endogenous Brn3b Expression. [PDF]

, 2019
Brn3b (Pou4f2) is a class-4 POU domain transcription factor known to play central roles in the development of different neuronal populations of the Central Nervous System, including retinal ganglion cells (RGCs), the neurons that connect the retina with ...
Cheema, Simranjeet K, La Torre, Anna, Mercado-Ayon, Yesica, Miltner, Adam M, Zawadzki, Robert J, Zhang, Pengfei   +5 more
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Incidence and outcomes of ocular hypertension from rhegmatogenous retinal detachment surgery in the acute postoperative setting

Clinical Ophthalmology, 2019
Albert John Bromeo, Nilo Vincent FlorCruzDepartment of Ophthalmology and Visual Sciences, Philippine General Hospital, University of the Philippines Manila, Manila, PhilippinesCorrespondence: Albert John BromeoSentro Oftalmologico Jose Rizal, Philippine ...
Bromeo AJ, FlorCruz NV
doaj  

Trail Making Test performance contributes to subjective judgment of visual efficiency in older adults [PDF]

, 2015
Introduction: The determinant factors that influence self-reported quality of vision have yet to be fully elucidated. This study evaluated a range of contextual information, established psychophysical tests, and in particular, a series of cognitive tests
Abdulrab, Anstey, Austin, Ball, Ball, Brant, Cabeza, Charalampidou, Cronin-Golomb, Crowe, Dufouil, D’Elia, Edwards, El-Gasim, Faubert, Fors, Grady, Hidalgo, Humes, Kearney, Keay, Kempen, Klein, Lindenberger, Lindenberger, Loughman, Madden, Owsley, Ponds, Rogers, Rubin, Rubin, Salthouse, Salthouse, Salthouse, Salthouse, Sanchez-Cubillo, Sekuler, Tejeria, Treisman, Wolfe   +40 more
core   +3 more sources

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma

Cell Death and Disease, 2022
Ocular hypertension is a significant risk factor for vision loss in glaucoma due to the death of retinal ganglion cells (RGCs). This study investigated the effects of the antiapoptotic peptides peptain-1 and peptain-3a on RGC death in vitro in rat ...
Mi-Hyun Nam, Dorota L. Stankowska, Gretchen A. Johnson, Rooban B. Nahomi, Mina B. Pantcheva, Ram H. Nagaraj   +5 more
doaj   +1 more source

Prevalance study of glaucoma in Malta and Gozo [PDF]

, 1992
A glaucoma survey was carried out in Malta and Gozo. Using non-contact pulseair tonometer, 2245 participants selected on a random basis, aged 40 years and above, were examined and 3.29% were found to have glaucoma.
Agius Muscat, Hugo, Blagojevic, Milan, Cachia, John, Soler, Richard   +3 more
core