Results 111 to 120 of about 1,619,173 (297)

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Gut Neuropathies and Intestinal Motility Disorders

Background: The enteric nervous system plays a key role in the coordination of gastrointestinal motility together with sympathetic, parasympathetic, and extrinsic sensory pathways.
Wattchow, David A., De Giorgio, Roberto, Dinning, Phil G., Brookes, Simon J. H., Spencer, Nick J., Costa, Marcello   +5 more
core   +1 more source

Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez, Amy Tam, Siofra Carty, Monica Ferrer Socorro, Kathryn Yang, Darius Ebrahimi‐Fakhari   +5 more
wiley   +1 more source

Walsh & Hoyt: Ocular Motor Dysfunction in Early HIV Encephalopathy

, 2005
Disorders of ocular motility, fixation, and alignment may occur in patients with AIDS. As noted previously, they may occur as a consequence of the HIV infection itself or secondary to infection or tumor that affects the ocular motor ...
Jacqueline Winterkorn, MD, PhD (1947-2015); Rochelle S. Zak, MD
core  

Comparison of gas-sensing capsule with wireless motility capsule in motility disorder patients

Background/Aims Motility disorders are prevalent, often leading to disrupted regional or whole gut transit times. In this study, we conducted a comparative analysis between the wireless motility capsule and an innovative gas-sensing capsule to evaluate ...
Ho, Vincent (R16852), Burgell, Rebecca, Zhou, Jerry (R17741), Gibson, Peter R., Thwaites, Phoebe A.   +4 more
core   +1 more source

Inferior rectus muscle rupture due to orbital trauma

Revista Brasileira de Oftalmologia
A 48-year-old patient with blunt periorbital trauma presented with vertical strabismus and diplopia secondary to inferior rectus muscle avulsion. After ophthalmologic and CT scan evaluation, early surgical treatment with anatomical restoration led to ...
Leonardo Landó, Tauan de Oliveira, Jomar Cleison de Rezende   +2 more
doaj   +1 more source

Improving the Diagnostic Accuracy of Plasma Alzheimer's Disease Biomarkers With Objective and Subjective Cognitive Screening

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Blood‐based biomarkers are increasingly used to identify Alzheimer's disease (AD) pathology and may play an important role in early disease screening and participant selection for clinical trials. However, their performance across stages of cognitive impairment remains unclear. This study examined whether plasma biomarkers differ in
Maryam Abdolmaleki, Leslie S. Gaynor, Dandan Liu, Timothy J. Hohman, Katherine A. Gifford, Henrik Zetterberg, Angela L. Jefferson, Corey J. Bolton   +7 more
wiley   +1 more source

Ocular Neuromyotonia and Superior Oblique Myokymia

, 1994
Disordered axonal function is arguably re sponsible for two unusual ocular motility disorders, ocular neuromyotonia and superior oblique myokymia. The discussion which follows will focus on the clinical features, presumed pathophysiology and treatment of
William T. Shults, MD
core  

Parkinson Disease Subtype Stability and Eventual Convergence

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok, Christina N. Lessov‐Schlaggar, Abdulmunaim M. Eid, Erin R. Foster, Baijayanta Maiti, Hailee Domash, Helen Hwang, Richard J. Perrin, Paul T. Kotzbauer, Joel S. Perlmutter, Meghan C. Campbell   +10 more
wiley   +1 more source

Ocular motility and functional disorders in congenital ptosis

, 2000
AMAÇ: Konjenital pitoziste göz hareket bozuklukları, binoküler görme, şaşılık, anizometropi, ambliyopi gibi fonksiyonel bozukluklar ile diğer kapak anomalilerinin sıklığı araştırıldı.
Ayşe Yağcı, Sait Eğrilmez, Süheyla Köse, Kemal Pamukçu   +3 more
core