Results 81 to 90 of about 12,044 (250)

Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 997-1004, April 2026.
Extended interval dosing regimens of immune checkpoint inhibitors have been implemented widely. However, their approval was mainly based on pharmacokinetic modeling and simulations. Consequently, comparative safety data of extended interval dosing regimens in a real‐world setting are limited.
Ruben Malmberg, Maaike M. Hofman, Fatima Ashad, Alaa Daloul, Stefani Oosterveld, Edwin A. Basak, Esther Oomen‐de Hoop, Astrid A. M. van der Veldt, Arjen Joosse, Roelof W. F. van Leeuwen, Ron H. J. Mathijssen   +10 more
wiley   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Thymic mass in an elderly male patient with myasthenia gravis: A rare presentation

Radiology Case Reports
Myasthenia gravis is an acquired neuromuscular disorder characterized by weakness of the extra-ocular muscles, which progresses to generalized weakness of the voluntary muscles and fatigability.
Anshul Sood, MBBS, Gaurav Vedprakash Mishra, MBBS, MD, Shreya Khandelwal, MBBS, Nishtha Manuja, MBBS, Manasa Suryadevara, MBBS   +4 more
doaj   +1 more source

Acute Bilateral Ophthalmoplegias [PDF]

, 1977
Bilateral ophthalmoplegia is that condition of weakness or paralysis involving one or more ocular muscles in each eye. Its sudden appearance due to an acute ocular myopathy is indeed unusual. Swash reported a single patient with acute necrotizing orbital
Selhorst, John B.
core   +1 more source

Sneddon's syndrome: clinical and laboratory analysis of 10 cases. [PDF]

, 2004
Sneddon's syndrome is characterized by livedo reticularis and cerebrovascular lesions. We report the cases of women (mean age, 36.2 +/- 8.1 years) diagnosed with Sneddon's syndrome based on the presence of livedo reticularis and characteristic ...
Akyol, Melih, Akyuz, Aytekin, Bolayir, Ertugrul, Erdogan, Haydar, Kugu, Nesim, Yilmaz, Abdulkerim   +5 more
core   +1 more source

Myasthenia gravis following the initiation of statin therapy: A multinational self‐controlled case series study

Journal of Internal Medicine, Volume 299, Issue 4, Page 502-514, April 2026.
Abstract Background Evidence regarding the risk of new‐onset myasthenia gravis (MG) following statin therapy initiation is limited. Objectives To investigate this potential adverse effect using multinational real‐world population‐based data. Methods A self‐controlled case series (SCCS) study was conducted using electronic medical records and claims ...
Vincent Ka Chun Yan, Wanchun Xu, Yuta Taniguchi, Kwun Kei Fung, Koon Ho Chan, Gary Kui Kai Lau, Celine Sze Ling Chui, Francisco Tsz Tsun Lai, Xue Li, Masao Iwagami, Rie Masuda, Nanako Tamiya, Sreemanee Raaj Dorajoo, Jing Wei Neo, Esther Wai Yin Chan, Ian Chi Kei Wong, Eric Yuk Fai Wan   +16 more
wiley   +1 more source

An Atypical Case of Myasthenia Gravis: Purely Bulbar in a Young Male

McGill Journal of Medicine, 2020
Myasthenia Gravis (MG), an uncommon autoimmune syndrome caused by the failure of neuromuscular transmission, results from bind- ing of autoantibodies to proteins that are involved in signaling at the neuromuscular junction (1).
Muhammad Amer Saleem, Faizan Pervaiz, Anum Yousaf, Muhammad Amer Saleem   +3 more
doaj  

Controversies in Ocular Myasthenia Gravis

Frontiers in Neurology, 2020
Myasthenia gravis (MG) with symptoms limited to eye muscles [ocular MG (OMG)] is a rare disease. OMG incidence varies according to ethnicity and age of onset.
Amelia Evoli, Amelia Evoli, Raffaele Iorio, Raffaele Iorio   +3 more
doaj   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 581-592, March 2026.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih, Sara Samadzadeh, Charlotte Bereuter, Seyedamirhosein Motamedi, Claudia Chien, Pablo Villoslada, Hadas Stiebel‐Kalish, Nasrin Asgari, Yang Mao‐Draayer, Marius Ringelstein, Joachim Havla, Marco Aurélio Lana Peixoto, Ho Jin Kim, Jacqueline Palace, Maria Isabel Leite, Srilakshmi M. Sharma, Fereshteh Ashtari, Rahele Kafieh, Lekha Pandit, Orhan Aktas, Philipp Albrecht, Letizia Leocani, Itay Lotan, Sasitorn Siritho, Jérôme de Seze, Romain Marignier, Caroline Froment Tilikete, Denis Bernardi Bichuetti, Ivan Maynart Tavares, Ayse Altintas, Anu Jacob, Saif Huda, Ibis Soto de Castillo, Lawrence J. Cook, Michael R. Yeaman, Axel Petzold, Alexander U. Brandt, Friedemann Paul, Frederike C. Oertel, Hanna G. Zimmermann, with the Guthy Jackson Charitable Foundation—International Clinical Consortium and CROCTINO Collaborators   +40 more
wiley   +1 more source

Presynaptic congenital myasthenic syndrome with altered synaptic vesicle homeostasis linked to compound heterozygous sequence variants in RPH3A. [PDF]

, 2018
BackgroundMonogenic defects of synaptic vesicle (SV) homeostasis have been implicated in many neurologic diseases, including autism, epilepsy, and movement disorders.
Burns, Chapman, Chung, Corbalan-Garcia, Cossins, Coudevylle, Deák, Engel, Engel, Foletti, Herrmann, Kato, Kochubey, Palace, Schlüter, Shen, Shen, Shirataki, Staunton, Sun, Tsuboi   +20 more
core   +1 more source