Results 81 to 90 of about 12,063 (227)

Corneal Biomechanics Determination in Healthy Myopic Subjects

Journal of Ophthalmology, 2016
Purpose. To determine the corneal biomechanical properties by using the Ocular Response Analyzer™ and to investigate potential factors associated with the corneal biomechanics in healthy myopic subjects. Methods. 135 eyes from 135 healthy myopic subjects
Kunliang Qiu, Xuehui Lu, Riping Zhang, Geng Wang, Mingzhi Zhang   +4 more
doaj   +1 more source

Correlation of Corneoscleral Membrane Biomechanical Properties and Eye Morphometric Parameters in Patients with Primary Open-Angle Glaucoma

Oftalʹmologiâ, 2019
Purpose: to study a correlation between morphometric parameters of the eye and tonometry data, taking into account viscoelastic properties of the cornea in patients with primary open-angle glaucoma (POAG), as well as in practically healthy individuals ...
B. M. Aznabaev, A. Sh. Zagidullina, I. A. Lakman, R. R. Islamova, R. R. Sattarova   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Assessment of corneal biomechanical properties and intraocular pressure with Ocular Response Analyzer in childhood myopia. [PDF]

, 2012
[[abstract]]"Background/aims The authors estimated the association between corneal biomechanical properties and axial length in myopic children and verified the relationship between axial length and intraocular pressure (IOP). Methods This cross-sectional
Pei-Yao Chang;Shu-Wen Chang;Jiun-Yi Wang
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Assessment of corneal biomechanical properties and intraocular pressure with Ocular Response Analyzer in childhood myopia [PDF]

, 2009
[[abstract]]Background/aims The authors estimated the association between corneal biomechanical properties and axial length in myopic children and verified the relationship between axial length and intraocular pressure (IOP). Methods This cross-sectional
Pei-Yao Chang;Shu-Wen Chang;Jiun-Yi Wang
core  

Corneal Biomechanics: A Paradigm shift in Studying Corneal Pathology

Delhi Journal of Ophthalmology, 2017
Biomechanics links corneal structure to its function. An area of intense research, corneal biomechanics can distinguish normal from ectatic corneas and has applications in various fields including cataract surgery, intraocular pressure measurement and ...
Shruti Kochar Maru, Tushar Grover, Rohit Shetty   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Corneal biomechanics in patients with allergic conjunctivitis

Indian Journal of Ophthalmology
Allergic conjunctivitis (AC) comprises a group of conditions triggered by environmental allergens, substantially diminishing the quality of life, particularly among children and adolescents.
Wan Haslina Wan Abdul Halim, Mohd Ihsan Jamaludin, Teck Chee Cheng   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source