Results 81 to 90 of about 49,154 (213)

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño, Shekeeb S. Mohammad, Rajeshwar Reddy Angiti, Velda Han, Michel Tchan, Russell C. Dale, Victor S.C. Fung   +6 more
wiley   +1 more source

Identification of Functional Cell Groups in the Abducens Nucleus of Monkey and Human by Perineuronal Nets and Choline Acetyltransferase Immunolabeling

Frontiers in Neuroanatomy, 2018
The abducens nucleus (nVI) contains several functional cell groups: motoneurons of the singly-innervated twitch muscle fibers (SIF) and those of the multiply-innervated muscle fibers (MIF) of the lateral rectus muscle (LR), internuclear neurons (INTs ...
Anja K. E. Horn, Anja K. E. Horn, Annie Horng, Norbert Buresch, Ahmed Messoudi, Wolfgang Härtig   +5 more
doaj   +1 more source

Characterization of genetic differences within the centrally-projecting Edinger-Westphal nucleus of C57BL/6J and DBA/2J mice by expression profiling

Frontiers in Neuroanatomy, 2012
Detailed examinations of the midbrain Edinger-Westphal nucleus (EW) revealed the existence of two distinct nuclei. One population of preganglionic neurons was found to control oculomotor functions (EWpg), and a separate population of centrally-projecting
William J Giardino, Dawn M Cote, Ju eLi, Andrey E Ryabinin   +3 more
doaj   +1 more source

Spatial but not oculomotor information biases perceptual memory. Evidence from face perception and cognitive modeling [PDF]

, 2017
Recent research put forward the hypothesis that eye movements are integrated in memory representations and are reactivated when later recalled. However, “looking back to nothing” during recall might be a consequence of spatial memory retrieval.
Lobmaier, Janek S., Wantz, Andrea L., Senn, Walter, Mast, Fred W.   +3 more
core   +1 more source

Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys

eLife
The subthalamic nucleus (STN) is a part of the indirect and hyperdirect pathways in the basal ganglia (BG) and has been implicated in movement control, impulsivity, and decision-making.
Kathryn Branam, Joshua I Gold, Long Ding
doaj   +1 more source

From Uncertainty to Pathogenicity: Resolving a CSF1R Variant of Uncertain Significance Using Long‐Read Transcriptomics

Movement Disorders, EarlyView.
Abstract Background CSF1R‐related disorder (CSF1R‐RD) is a severe autosomal dominant leukoencephalopathy characterized by progressive cognitive, neuropsychiatric, and motor decline. Although genetic testing is widely available, numerous likely pathogenic variants in CSF1R frequently remain classified as variants of uncertain significance (VUS ...
Charles Wade, Kylie Montgomery, Gabriela E. Jones, Peter Sellars, Akram A. Hosseini, Simon Paine, Henry Houlden, Mina Ryten, David S. Lynch   +8 more
wiley   +1 more source

Autoimmune Diseases and the Vestibular and Oculomotor System: Clinical Presentation, Diagnosis, and Treatment

Journal of Eye Movement Research
Vertigo, dizziness, and oculomotor disturbances may occur as manifestations of immune-mediated disorders affecting the inner ear, central vestibular pathways, or multisystem autoimmune disease. Although uncommon, these conditions are clinically important
Felix K. Schwarz, Gerald Wiest, Paulus Rommer   +2 more
doaj   +1 more source

Prelacrimal Transmaxillary‐Orbital Approach for Resection of Lateral Extraconal Orbital Cavernous Hemangioma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Endoscopic orbital surgery is likely a reasonable option for patients with orbital cavernous hemangiomas (OCH) medial to the optic nerve (ON). The endoscopic resection of OCH lateral to the ON is extremely challenging. Zhou et al. first described the endoscopic prelacrimal recess approach (PLRA) for the management of the maxillary sinus and ...
Zhen‐Xiao Huang, Xiao‐Qing Zhang, Bing Zhou   +2 more
wiley   +1 more source

The Role of Concussion History and Biological Sex on Pupillary Light Reflex Metrics in Adolescent Rugby Players: A Cross-Sectional Study

Sports
Background: Concussion examination is based primarily on clinical evaluation and symptomatic reporting. Pupillary light reflex (PLR) metrics may provide an objective physiological marker to inform concussion diagnosis and recovery, but few studies have ...
Connor McKee, Mark Matthews, Alan Rankin, Chris Bleakley   +3 more
doaj   +1 more source

Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Otolith is a critical component of the peripheral vestibular system responsible for detecting linear acceleration. Dysfunction of the otolith organs can lead to vertigo, balance disturbances, and gaze instability. By elucidating the physiological foundations and evaluating both current and emerging methods for assessing otolith ...
Shun Zhou, E Tian, Hua‐Jing Yang, Jun Wang, Zhao‐Qi Guo, Jing‐Yu Chen, Wan‐Di Xu, Jia‐Qi Guo, Zhang‐Hong Zhou, Shi‐Yu Shi, Xi‐Xi Yu, Xin‐Bo Gao, Ni Zhai, Xin Ma, Qing Zhang, Yi‐Sheng Lu, Su‐Lin Zhang   +16 more
wiley   +1 more source