Results 41 to 50 of about 3,871,958 (252)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Odor-active compounds from the gonads of Mesocentrotus nudus sea urchins fed Saccharina japonica kelp

, 2020
Gonad size, color, texture and taste of Mesocentrotus nudus sea urchins collected from a barren can be improved by a short-term cage culture while being fed fresh Saccharina japonica kelp during May–July. We investigated the effect of S. japonica feeding
Yukio Agatsuma (6169940), Eri Inomata (6169934), Atsuko Kokubun (8720232), Yoichi Sato, Yukio Agatsuma, Satomi Takagi, Satomi Takagi (8720229), Atsuko Kokubun, Yoichi Sato (1833145), Eri Inomata   +9 more
core   +1 more source

Development and field evaluation of a synthetic mosquito lure that is more attractive than humans. [PDF]

, 2010
BACKGROUND\ud \ud Disease transmitting mosquitoes locate humans and other blood hosts by identifying their characteristic odor profiles. Using their olfactory organs, the mosquitoes detect compounds present in human breath, sweat and skins, and use these
Killeen, G.F., Ngonyani, Hassan, Fredros O Okumu, Edgar Mbeyela, Smallegange, R.C., Moore, Sarah J., Ogoma, Sheila, Munk, Cristina, Mukabana, Wolfgang R., Ngonyani, H., Mbeyela, Edgar, Ogoma, S., Cristina Munk, Emmanuel Titus, Hassan Mshinda, Moore, S.J., Sheila Ogoma, Killeen, Gerry F, Sarah J Moore, Wolfgang R Mukabana, Takken, W., Okumu, Fredros O, Mshinda, Hassan, Mukabana, W.R., Okumu, Fredros O., Okumu, F.O., Lubandwa Biswaro, Moore, Sarah J, Munk, C., Smallegange, Renate C, Gerry F Killeen, Renate C Smallegange, Titus, E., Titus, Emmanuel, Takken, Willem, Mukabana, Wolfgang R, Hassan Ngonyani, Mbeyela, E., Killeen, Gerry F., Mshinda, H., Biswaro, Lubandwa, Biswaro, L., Smallegange, Renate C., Willem Takken   +43 more
core   +1 more source

Chemical Studies of Yellow Tamarillo (Solanum betaceum Cav.) Fruit Flavor by Using a Molecular Sensory Approach

Molecules, 2016
The odor-active volatile compounds of yellow tamarillo fruit (S. betaceum Cav.) were identified and quantified by using a sensomics approach, combining a gentle volatile extraction (solvent-assisted flavor evaporation (SAFE)), gas chromatography-mass ...
Juliana María García, Laura Juliana Prieto, Alirio Guevara, Diana Malagon, Coralia Osorio   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Joint European Compound Library:boosting precompetitive research [PDF]

, 2015
The Joint European Compound Library (JECL) is a new high-throughput screening collection aimed at driving precompetitive drug discovery and target validation.
Hopkins, Andrew L., Jérémy Besnard, Jones, Philip S., Philip S. Jones, Pannifer, Andrew D., Andrew L. Hopkins, Besnard, Jérémy, Andrew D. Pannifer   +7 more
core   +1 more source

Identification of Key Aroma-Active Compounds in Plum, Jujube, and Grape Extracts via GC×GC-O-TOF-MS, GC-MS, Aroma Recombination and Omission Tests

Separations
Fruity natural flavors are widely used in food, cosmetics, and tobacco products, and their flavor profiles directly affect the sensory quality of the final products.
Ruiyang Chen, Qinghui Jia, Anzhen Fu, Fan Yang, Yixin Dai, Jingzhe Sun, Liya Liu, Ye Liu, Shuang Bi   +8 more
doaj   +1 more source

Characterization of meat quality traits, fatty acids and volatile compounds in Hu and Tan sheep

Frontiers in Nutrition, 2023
Sheep breed has a major influence on characteristics of meat quality and intramuscular fat (IMF), however, studies into the relationship between sheep breed and meat quality traits rarely consider the large variation in IMF within breed.
Jing Li, Jing Li, Chaohua Tang, Chaohua Tang, Youyou Yang, Youyou Yang, Ying Hu, Ying Hu, Qingyu Zhao, Qingyu Zhao, Qing Ma, Xiangpeng Yue, Fadi Li, Junmin Zhang, Junmin Zhang   +14 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Odor in immersive environments

, 2022
S.139-140Immersive environments provide a computer generated virtual reality for their users. They are applied in various fields such as engineering, marketing and sales, education and training, therapy or entertainment.
Dangelmaier, Manfred, Blach, Roland
core   +1 more source