Results 51 to 60 of about 372,932 (302)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Chemical Characterization of Human Body Odor Headspace Components

Separations
This study focused on evaluating human body odor volatiles using a chamber approach. Ten participants were asked to sit inside the chamber for 1 h, while using SPME as the extraction technique for vapor sampling.
A. Celeste Medrano, Ariela Cantu, Edgar O. Aviles-Rosa, Nathaniel J. Hall, Michele N. Maughan, Jenna D. Gadberry, Paola A. Prada-Tiedemann   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Accidental awareness during general anaesthesia

Advances in Perioperative Care
This narrative vignette illustrates accidental awareness during general anaesthesia through the case of a 40-year-old woman who experienced vivid recall of intraoperative events during myomectomy, including suffocation sensations and abdominal pain ...
Peter Odor
doaj   +2 more sources

Odors Emitted from Biological Waste and Wastewater Treatment Plants: A Mini-Review

Atmosphere, 2022
In recent decades, a new generation of waste treatment plants based on biological treatments (mainly anaerobic digestion and/or composting) has arisen all over the world.
Daniel González, David Gabriel, Antoni Sánchez   +2 more
doaj   +1 more source

Sensory memory for odors is encoded in spontaneous correlated activity between olfactory glomeruli [PDF]

, 2006
Sensory memory is a short-lived persistence of a sensory stimulus in the nervous system, such as iconic memory in the visual system. However, little is known about the mechanisms underlying olfactory sensory memory.
Galizia, C. Giovanni, Galán, Roberto F., Herz, Andreas V. M., Menzel, Randolf, Weidert, Marcel   +4 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Rational Design of Peptide-Functionalized Surface Plasmon Resonance Sensor for Specific Detection of TNT Explosive

Sensors, 2017
In this study, a rationally-designed 2,4,6-trinitrotoluene (TNT) binding peptide derived from an amino acid sequence of the complementarity-determining region (CDR) of an anti-TNT monoclonal antibody was used for TNT detection based on a maleimide ...
Jin Wang, Masaki Muto, Rui Yatabe, Takeshi Onodera, Masayoshi Tanaka, Mina Okochi, Kiyoshi Toko   +6 more
doaj   +1 more source

Language of smell: Tracing some cross-cultural insights from past and present

Frontiers in Food Science and Technology, 2023
It is assumed that the human sense of smell is inferior to vision. This framework of underdeveloped human olfaction can be mainly attributed previously to its historical demotion of it by the Western, quasi-scientific ideas, and evolutionary narratives ...
Chetan Sharma
doaj   +1 more source

Hand tool permits shrink sizing of assembled tubing [PDF]

, 1966
Portable tool sizes tubing ends without disassembling the tubing installation. The shrink sizing tool is clamped to the tubing and operated by a ratchet wrench.
Millett, A., Odor, M.
core   +1 more source