The Chemical Fingerprint of Smokeless Powders: Insights from Headspace Odor Volatiles
PowdersSmokeless powders are a commonly used low explosive within the ammunition industry. Their ease of purchase has allowed criminals to use these products to build improvised explosive devices.
Miller N. Rangel +6 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Odor-induced theta, beta, and gamma oscillations are evident across a range of olfactory tasks.
, 2022 Shown are spectrograms from 2 participants (P8 and P9) who performed 3 different olfactory tasks including a detection task (top row), an edibility assessment task (middle row), and an odor naming task (bottom row).
Jessica W. Templer (11909933) +7 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Odors Emitted from Biological Waste and Wastewater Treatment Plants: A Mini-Review
Atmosphere, 2022 In recent decades, a new generation of waste treatment plants based on biological treatments (mainly anaerobic digestion and/or composting) has arisen all over the world.
Daniel González +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Olfactory Signatures of Bladed Weapons: Characterization and Implications for Canine Detection
ChemosensorsKnife crime has increased globally, yet the effectiveness of current detection methods used by law enforcement is often limited in operational settings. This challenge highlights the need for innovative detection approaches.
Courtney Ann McGuire +3 more
doaj +1 more source
Language of smell: Tracing some cross-cultural insights from past and present
Frontiers in Food Science and Technology, 2023 It is assumed that the human sense of smell is inferior to vision. This framework of underdeveloped human olfaction can be mainly attributed previously to its historical demotion of it by the Western, quasi-scientific ideas, and evolutionary narratives ...
Chetan Sharma
doaj +1 more source
Innate preference for host-odor blends modulates degree of anthropophagy of Anopheles gambiae sensu lato (Diptera: Culicidae) [PDF]
, 2001 In field studies, Anopheles gambiae Giles sensu stricto obtains most blood meals from humans, whereas Anopheles quadriannulatus Theobald bites predominantly bovids. We investigated whether host odors modulate the host preference of these mosquito species.
Braks, M.A.H., Dekker, T., Takken, W.
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source