Results 81 to 90 of about 1,077,330 (235)

Altered Expression of Chemosensory and Odorant Binding Proteins in Response to Fungal Infection in the Red Imported Fire Ant, Solenopsis invicta [PDF]

, 2021
Wei Zhang, Almudena Ortiz‐Urquiza, Nemat O. Keyhani   +2 more
openalex   +1 more source

Ligand binding and homology modelling of insect odorant‐binding proteins [PDF]

Physiological Entomology, 2014
Abstract This review describes the main characteristics of odorant‐binding proteins ( OBP s) for homology modelling and presents a summary of structure prediction studies on insect OBP s, along with the steps involved and some ...
Venthur, H., Mutis, A., Zhou, J-J., Quiroz, A.   +3 more
openaire   +1 more source

Exploring the Potentiality of Natural Products from Essential Oils as Inhibitors of Odorant-Binding Proteins: A Structure- and Ligand-Based Virtual Screening Approach To Find Novel Mosquito Repellents

ACS Omega, 2019
Odorant-binding proteins (OBPs) are the main olfactory proteins of mosquitoes, and their structures have been widely explored to develop new repellents. In the present study, we combined ligand- and structure-based virtual screening approaches using as a
K. D. da Costa, J. M. Galúcio, C. H. S. da Costa, Amanda Ruslana Santana, Vitor dos Santos Carvalho, L. D. do Nascimento, A. H. Lima e Lima, Jorddy Neves Cruz, C. Alves, J. Lameira   +9 more
semanticscholar   +1 more source

Ligand binding and partial characterization of sex-specifically expressed lipocalins of submandibular and lacrimal glands of Syrian hamsters

Scientific Reports
Lipocalins are abundantly expressed secretory proteins that perform diverse roles such as ligand-transport, immunomodulation, cell-signaling, chemical communication etc.
Ved Prakash Dubey, Prabir Kumar De
doaj   +1 more source

Molecular bases of insect odorant receptor function: specificity and evolution

Biological Reviews, Volume 101, Issue 2, Page 1036-1049, April 2026.
ABSTRACT Insect odorant receptors (ORs) are a class of chemoreceptors that insects use to detect volatile cues in their environment. In recent years, major advances in the field of structural biology have made it possible to obtain the first structures of insect ORs.
Zibo Li, Abhinob Baruah, Sridevi Bhamidipati, Nicolas Montagné, Emmanuelle Jacquin‐Joly, Camille Meslin   +5 more
wiley   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

The genome and stage‐specific transcriptomes of the carrot weevil, Listronotus oregonensis, reveal adaptive mechanisms for host specialisation and symbiotic interactions

Insect Molecular Biology, Volume 35, Issue 2, Page 126-138, April 2026.
Comprehensive genome and stage‐specific transcriptomes reveal 14,637 genes in Listronotus oregonensis, advancing genetic insights into a key agricultural pest. Compared with related species, L. oregonensis exhibits reduced chemoreceptor gene families but expanded detoxification gene clusters, reflecting its narrow host range and adaptability.
Dave T. Ste‐Croix, Annie‐Ève Gagnon, Benjamin Mimee   +2 more
wiley   +1 more source

Identification of Genes Involved in Chemoreception in Plutella xyllostella by Antennal Transcriptome Analysis

Scientific Reports, 2017
Perception of environmental and habitat cues is of significance for insect survival and reproduction. Odor detection in insects is mediated by a number of proteins in antennae such as odorant receptors (ORs), ionotropic receptors (IRs), odorant binding ...
Shiyong Yang, Depan Cao, Guirong Wang, Yang Liu   +3 more
doaj   +1 more source

ShenQi DiHuang Decoction (SQDHD) Ameliorates Neuroinflammation and Neuropsychiatric Manifestations in Pristane Induced Lupus Mice via Blocking JAK1‐STAT3 Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
SQDHD exerts neuroprotective effects and alleviates behavioral deficits in PIL mice, likely by inhibiting the JAK1‐STAT3 pathway in activated CVECs. These findings underscore the therapeutic potential of SQDHD and establish it as a promising candidate for the treatment of NPSLE.
Jie Chen, Chumiao Cui, Fei Xu, Jiayan Feng, Jingyu Chen, Xueru Wang, Hui Yuan, Chenye Jin, Yutian Li, Yang Yun   +9 more
wiley   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, Volume 46, Issue 2, Page 445-474, March 2026.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source