Results 51 to 60 of about 13,485,768 (280)

Estudio Axiológico del ODS 4: Educación de Calidad

Revista Internacional de Educación para la Justicia Social
The documents that regulate or enact educational actions, whether at the local or global level, must take into account a integral perspective if they aim to guarantee quality education.
Rocío López-García-Torres, Elia Saneleuterio   +1 more
semanticscholar   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Recursos Educacionais Abertos e Agenda 2030. A Universidade Aberta de Portugal (UAb)

Ciência da Informação, 2020
Analisa-se a relevância do Projeto Recursos Educacionais Abertos (REA), desenvolvido pela Universidade Aberta de Portugal (UAb), para o cumprimento dos Objetivos do Desenvolvimento Sustentável, em particular: ODS 4 - Educação de Qualidade e ODS 17 ...
Madalena Carvalho
doaj  

Classification of Odontogenic Sinusitis: A Clinical-Based Phenotyping System to Guide Multidisciplinary Surgical Management. [PDF]

Laryngoscope Investig Otolaryngol
ABSTRACT Background Odontogenic sinusitis (ODS) is a condition that requires a multidisciplinary approach for successful treatment. Effective communication among the healthcare providers involved reduces the risk of errors and treatment failure. This study proposes a new ODS classification system to facilitate the communication of pivotal clinical ...
Sabatino L, Di Giovanni S, Pierri M, Bigliardo C, Mattaroccia M, Valentini M, Moffa A, Casale M, Lopez MA.   +8 more
europepmc   +2 more sources

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Zinc Fingers as Programmable Metalloprotein Scaffolds for Altering Pathogenic Biomolecular Phase Transitions

Advanced Science, EarlyView.
Modular zinc finger (ZF) metalloproteins function as programmable biomolecular scaffolds that modulate pathogenic amyloid assembly. Through direct protein–protein interactions, ZF arrays alter amyloid phase behavior and redirect β‐sheet fibrillization toward nontoxic aggregates.
Seongmin Park, Yunha Hwang, Jimin Kwak, Yuxi Lin, Hye‐Yeon Park, Eunju Nam, Jiyeon Han, Soyeon Park, Hyunyong Kim, Ju‐Eun Kim, Hyun Goo Kang, Jiyong Park, Young‐Ho Lee, Kyoung‐Shim Kim, Chul‐Ho Lee, Seung Jae Lee, Mi Hee Lim   +16 more
wiley   +1 more source

Automated Bacterial Identification and Morphological Feature Analysis in Low‐Dose Cryo‐EM Using YOLOv11

Advanced Intelligent Discovery, EarlyView.
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula, Lynnicia N. Massenburg, Spenser R. Brown, Amber N. Bible, Chanda R. Harris, Lance X. Zhang, Kiara Parker, Scott T. Retterer, Jennifer L. Morrell‐Falvey, Rama K. Vasudevan, Alexis N. Williams   +10 more
wiley   +1 more source

O papel da educação e formação profissional (VET) na concretização do Objetivo de Desenvolvimento Sustentável 4

Política e Gestão Educacional
Este estudo visa identificar o papel da Educação e Formação Profissional (EFP) na consecução do Objetivo de Desenvolvimento Sustentável 4 (ODS 4). Para este propósito, foi realizada uma revisão bibliográfica focada em políticas para examinar a relação ...
Esen Sucuoglu , Nesrin M. Bahcelerli
doaj   +1 more source

The Influence of Aluminum Content on Oxidation Resistance of New-Generation ODS Alloy at 1200 °C

Metals, 2020
The aim of the paper is to evaluate the effect of aluminum content on the oxidation resistance of new-generation of oxide dispersion strengthened (ODS) alloy at 1200 °C.
L. Stratil, V. Horník, P. Dymáček, P. Roupcová, J. Svoboda   +4 more
semanticscholar   +1 more source