Results 131 to 140 of about 664,295 (249)

Investigation of ACE and DPP‐IV Inhibitory Potential of Peptides Obtained From Hazelnut Protein Hydrolysates in Food Supplement Applications

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
Production of peptide molecules from hazelnut cake using proteolytic enzymes and ultrafiltration methods. Exploration of antioxidant activities, DPP‐IV and ACE inhibitory properties of these molecules and their evaluation in food supplement applications.
Sebahat Şişman   +3 more
wiley   +1 more source

A Retrospective Study of Adult and Pediatric D‐Dimer Tests to Identify Opportunities for Improved Utilization

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 2, Page 392-401, April 2026.
ABSTRACT Introduction D‐dimers are produced by lysis of cross‐linked fibrin. In children, D‐dimer testing is used to evaluate disseminated intravascular coagulation (DIC) and some inflammatory states, but its use is not validated for screening or ruling out suspected venous thromboembolic events (VTE).
Rabab Al Dawood   +4 more
wiley   +1 more source

Towards a sustainable rare disease and orphan drug ecosystem in Saudi Arabia: policy insights from a multi-stakeholder workshop

open access: yesFrontiers in Pharmacology
IntroductionRare diseases (RDs) present significant challenges worldwide, including Saudi Arabia (SA), where access to orphan drugs (ODs) is suboptimal.
Ghada Mohammed Abozaid   +5 more
doaj   +1 more source

A Novel Mouse Model of Sympathoadrenal Catecholamine Deficiency by Ablation of the Tyrosine Hydroxylase Gene With Slc6a4‐Cre

open access: yesJournal of Neurochemistry, Volume 170, Issue 4, April 2026.
Tyrosine hydroxylase (TH) is a rate‐limiting enzyme for catecholamine synthesis. In this study, we generated a novel Th gene conditional knockout mouse line by crossing Th‐flox mice with Slc6a4‐Cre mice. To our surprise, TH expression was largely lost in the adrenal medulla and sympathetic neurons in the conditional knockout mice.
Ryohei Ogawa   +4 more
wiley   +1 more source

Multiscale microstructure-based constitutive modeling of high-temperature creep rupture in post-irradiated ODS steels

open access: yesJournal of Materials Research and Technology
Oxide dispersion strengthened (ODS) steel exhibits the great potential as structural materials in nuclear energy production, owing to the complex interface between the oxide particles and the matrix to enhance the resistance of radiation damage. However,
Xiaobao Fu   +8 more
doaj   +1 more source

Artificial Intelligence in Gastrointestinal Motility Diagnostics: A Systematic Review

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
Artificial Intelligence shows strong potential to improve the accuracy, efficiency, and standardization of gastrointestinal motility diagnostics. In time, this will improve patient care, but for now the referenced studies throughout the GI tract lack the required rigor for clinical implementation. ABSTRACT Background The assessment of gastrointestinal (
Dylan Muggleston   +3 more
wiley   +1 more source

Biochemical Engineering Perspective on cGAS: From Enzyme Discovery to Potential Industrial Application

open access: yesChemBioChem, Volume 27, Issue 5, 13 March 2026.
This review examines the structural and enzymatic properties of cyclic GMP‐AMP synthase, including substrate promiscuity, homologs, and engineered variants. In addition, it evaluates potential expression systems for large‐scale enzyme production and analyzes reaction and purification strategies for the synthesis of cyclic dinucleotides to connect ...
Makram Fataeri, Katrin Rosenthal
wiley   +1 more source

Život na prostoru Viminacijuma od 5. do 12. veкa

open access: yes, 2022
Over several centuries, Viminacium represented one of the most important military strongholds on the Danube, in which the legion VII Claudia was stationed. In the 4th century, barbaric tribes frequently raiding the territory of the Empire, represented a permanent threat. The great defeat of the Roman army in 378 by Hadrianopolis made new raids possible,
openaire   +1 more source

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