Results 101 to 110 of about 98,650 (241)

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Refining the electroclinical phenotype of 15q11.2 microdeletion: EEG biomarker overlap with Angelman syndrome

Epileptic Disorders, EarlyView.
Abstract The 15q11.2 microdeletion is a chromosomal condition associated with a broad epileptic phenotype. It is differentiated from Angelman syndrome, which is typically a larger maternal deletion in an overlapping area. We describe a patient with a 15q11.2 microdeletion that has clinical and EEG biomarker features similar to those seen in Angelman ...
Hok Leong Chin, Joshua Chang, Douglas Nordli III   +2 more
wiley   +1 more source

Le rôle de la personnification de la nature dans la représentation des catastrophes naturelles : de L’Odyssée d’Homère à la climate-fiction contemporaine

Sociopoétiques
From Homer’s Odyssey to contemporary climate fiction, the perception of natural disasters within literature allows the analysis of some social reflection of the place that human beings hold in the cosmos. Through the reading of the Odyssey and three
Sofia MAVROGIANNI
doaj   +1 more source

Comprehensive Odyssey

, 2017
The zip folder holds the files of the proof of concept for my PhD dissertation: “Comprehensive Odyssey”, a digital critical repository of the Odyssey and its sources: Perspectives and Consequences.
Salvagni, Chiara (5295436), Salvagni, Chiara   +1 more
core   +1 more source

Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model

Epilepsia, EarlyView.
Abstract Objective γ‐Aminobutyric acidergic (GABAergic) parvalbumin‐positive (PV+) interneurons are critical for maintaining cortical inhibitory tone, with their dysfunction predictably leading to epilepsy. Rapid PV+ interneuron firing is essential for their normal function and is maintained in part by potassium voltage‐gated channels.
Sheryl Anne D. Vermudez, Mustafa Q. Hameed, Yongho Choe, Gabrielle E. McGinty, Amanda M. Liebhardt, Rui Lin, Benjamin Hui, Yini Liang, David J. Arce, Henry H. C. Lee, Mustafa Sahin, Alexander Rotenberg   +11 more
wiley   +1 more source

Gu Hongming's Eccentric Chinese Odyssey

Gu Hongming's Eccentric Chinese Odyssey is the first comprehensive study in English of Gu Hongming, both the private individual and the public cultural figure.
Du, Chunmei.
core  

Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events The ODYSSEY OUTCOMES Trial

, 2019
: BACKGROUND The ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) trial compared alirocumab with placebo, added to high-intensity or maximum-tolerated statin treatment, after acute
Chumburidze, Vakhtang, Toma, Mustafa, Ahuad Guerrero, Rodolfo A., Marcus, Jill, DeVore, Adam D., Goronja, Boris, Markov, Dimitar T., Morisset, Anne, Dong, Yugang, Harrison, Robert W., Alexander, John H., Perkins, Lynn, Codutti, Oscar R., Rossi, Paulo R. F., Ritt, Luiz Eduardo F., Midzic, Zlatko, Garrahy, Paul J., Vrolix, Mathias C. M., Jure, Horacio O., Collins, Nicholas, Sousa, Luciano, Novotny, Vojtech, Araneda, Guillermo, Sujjavanich, Darin, Persic, Viktor, Shi, Xubo, Muslibegovic, Adis, Pecin, Ivan, Kristensen, Kjeld S., Soopold, Ullar, Durak-Nalbantic, Azra, Motovska, Zuzana, Precoma, Dalton B., Nielsen, Peter Kaiser, Sassone, Sonia A., Bang, Lia E., Ramos Lopez, Gabriel Arturo, Xu, Biao, Zhou, Yujie, Dick, Ronald, Erglis, Andrejs, Pearce, Stephen, Striekwold, Harry, Jatin, Fernando G. Manzur, Li, Huanming, Prieto, Juan C., Colombo, Hugo R., Sabbah, Eric, Kalil, Renato, Hameed, Adnan, Prvulovic, Deiti, Soots, Mai, Dong, Shaohong, Machado, Leandro, Fong, Peter, Alves De Lima, Alberto E., Mahaffey, Kenneth W., Lopes, Renato D., Horowitz, John, Fazlibegovic, Emir, Vejar, Margarita, Zheng, Yang, Hrabar, Adrian D., Lin, Wenhua, de Silva, Pedro G. M. B., Zweiker, Robert, Duda, Norberto, Cestari, Horacio G., Jones, William Schuyler, Schwartz, Gregory G., Pincetti, Cristian, Yusoff, Khalid, Nicolau, Jose C., Zdravko, Babic, Fell, David, de Souza, Juliana A., Dimov, Bojidar I., Ristic, Arsen D., Edelberg, Jay M., Steg, Ph. Gabriel, Olivares, Claudia, Gislason, Gunnar, Wollaert, Bart, Xu, Xiping, Bono, Julio O. E., Colquhoun, David, Xu, Yizhou, Hove, Jens D., Lai, Christopher, Zeiher, Andreas M., Yan, Andrew Tze-Kay, Vidotti, Maria H., Bata, Iqbal, Davidsen, Flemming, Raffo, Carlos A., Todorov, Georgi V., Zhao, Xingsheng, Arstall, Margaret A., Cools, Frank, De Salazar, Dora I. Molina, Herazo, Aristides Sotomayor, Lopez-Jaramillo, Patricio, Karpov, Yuri, Sherwood, Matthew W., Correa Flores, Roger M., Vizel, Saul, Patel, Chetan B., Marusincova, Ivana, Salomone, Rodolfo, Huber, Kurt, Yu, Yihua, Rogers, James F., Cleveland, David, Silva, Ricardo P., Harrington, Robert A., Zong, Wenxia, Hii, Chris L. S., Valgimigli, Marco, Guo, Ying, Zahger, Doron, Marx, Nikolaus, Li, Jianping, Mendoza, Jose L. Accini, Strozzi, Maja, Dorobantu, Maria, Ruiz, Ricardo L. Fernandez, Paterlini, Gustavo A., Luo, Zhurong, Lillis, Linda, Lin, Jinxiu, Zhang, Zheng, Armaganijan, Luciana, Claeys, Marc J., Ostadal, Petr, Hlatky, Mark A., Vervoort, Geert, Moriarty, Patrick M., Gosselin, Gilbert, Li, Xiang, Milicic, Davor, Brennan, J. Matthew, Cui, Lan, Silveira, Jose A., Su, Xi, Laucevicius, Aleksandras, Gomez Vilamajo, Oscar A., Hermans, Kurt, Meloni, Chiara, Vahula, Veiko, Yang, Xiangjun, Beauloye, Christophe, Halvorsen, Sigrun, Botelho, Roberto V., Higuera, Juan Diego, Giorgeto, Flavio E., Chen, Dandan, Qu, Baiming, Reis, Gilmar, Guneri, Sema, Chen, Yundai, Huidobro, Laura, Zheng, Zeqi, Wang, Jingfeng, Pesant, Yves, Szarek, Michael, Dombrowski, Keith, Kim, Sang-Hyun, Mincheva, Valentina M., Pojskic, Belma, Leung, Raymond, Lehman, Sam J., Tomulic, Vjekoslav, Berger, Rudolf, Kichukov, Kostadin N., Parkhomenko, Alexander, Leaes, Paulo E., Rodes-Cabau, Josep, Wei, Meng, Walichiewicz, Piotr Maria, Wang, Jian'An, Juonala, Markus, Fu, Guosheng, Pirenne, Bruno, Huang, Shi'An, Maron, David J., Ge, Junbo, Budaj, Andrzej, Zaidman, Cesar J., Sritara, Piyamitr, Starmer, Gregory, Souza, Weimar K. S. B., Montana, Oscar R., Montecinos, Humberto, Jiang, Weihong, Kolls, Bradley J., Larsen, John, Endsley, Patricia, Heinc, Petr, Vallejos, Julio A., Perez, Luis, Mileta, Dean, Eppinger, Arleen, Liberman, Alberto, Feitosa, Gilson S., Pordy, Robert, Clifton, Shaun, Kedev, Sasko, Caime, Guillermo D., Martsin, Kaja, Bagai, Akshay, Sy, Rody G., Drexel, Heinz, Roberts-Thomson, Philip, Feng, Yi, Davies, Richard, Patocchi, Cristian A., Fadlallah, Hussein, Johansen, Peter Betton, Cheng, Xiaoshu, Xu, Dingli, Spinar, Jindrich, de Silva, H. Asita, Terzic, Ibrahim, Lepage, Serge, Vallejo, Gregorio Sanchez, Kormann, Adrian, Jeppesen, Jorgen, Lopez, Ramos, Pimentel Filho, Pedro, Oqueli Flores, Romulo E., Alings, Marco, Hess, Connie Ng, Klausen, Ib C., Ding, Chunhua, Van Diepen, Sean F. P., Sinnaeve, Peter, Kong, David F., Abrantes, Jose Antonio M., Taskinen, Marja-Riitta, Garrido, Marcelo, MacDonald, Paul, Yuan, Zuyi, Kristjan, Arved, Xavier, Denis, Kiviniemi, Tuomas, Knowles, Joshua W., Castadot, Marc, Sasiela, William J., Bonfanti, Alberto J. Cadena, Blumberg, Eduardo D. S., Cerqueira, Maria Jose A. G., Nigro, Frank, Chen, Jiyan, Sijbrands, Eric J. G., Cartasegna, Luis R., Dion, Danielle, Garcia Brasca, Daniela F., Wang, Jianzhong, Cha, James, Frost, Lars, Michaud, Nicolas, Dalby, Anthony J., Neuenschwander, Fernando, Yanez, Mario, Stone, James, Tunon, Jose, Wilson, Matthew D., Hanotin, Corinne, Lazov, Petar V., Mathews, Robin, Chaitman, Bernard, Llois, Susana, Kaucak, Vladimir, Nielsen, Tonny, Hoppe, Uta, Bencic, Martina Lovric, Simoons, Maarten L., Mehta, Rajendra H., Morais, Joao, Liu, Shaowen, Mackinnon, Ignacio J., Bordonava, Anselmo P., Amuchastegui, Marcos, Costa, Fernando, Gotcheva, Nina N., Sikic, Jozica, Silva, Sandra I. Barrera, Fan, Zhongcai, Duran, Ruben O. Garcia, Naplava, Robert, Puymirat, Etienne, Caccavo, Alberto, Kaiser, Sergio, Duronto, Ernesto A., Lu, Qinghua, Aguirre, Arnoldo, Bahit, Maria Cecilia, Medrano Allende, Juan C., Podpera, Ivo, Taurio, Jyrki, Eliaschewitz, Freddy G., Coufal, Zdenek, Jukema, J. Wouter, Goodman, Shaun G., Stasek, Josef, Zizka, Jiri, Shah, Bimal R., Rosenson, Robert, Huang, Weijian, Schmidberg, Jorge M., Botia, Diana C. Luna, Ray, Kausik K., Hagstrom, Emil, Moryusef, Angele, White, Harvey D., Shaw, James, Wu, Chun, Lorenzatti, Alberto J., Yao, Zhuhua, Bittner, Vera A., Vico, Marisa L., Lopez, Rodrigo Botero, Luquez, Hugo A., Li, Ying, Arroyo, Julian A. Coronel, Raev, Dimitar H., Bustamante Labarta, Miguel H., Mehta, Shamir, Huikuri, Heikki, Vikman, Saila, Kim, Hyo Soo, Angel Hominal, Miguel, Zhang, Ruiyan, Nani, Sebastian, Aroney, Constantine, Li, Xiaodong, Sun, Yingxian, Waisman, Gabriel D., Michalaros, Yorghos L., Roe, Matthew T., Su, Guohai, Bhatt, Deepak L., Diaz, Ariel, Ducas, John, Zapata, Gerardo, Novaretto, Leonardo P., Nikolov, Fedya P., Olsson, Anders G., Kiss, Robert Gabor, Danchin, Nicolas, Liberopoulos, Evangelos, Alvarisqueta, Andres F., Sun, Yuemin, Tumbev, Haralin S., Dilic, Mirza, Kuchar, Jiri, Zhu, Jianhua, Berli, Mario A., Hoffer, Etienne, Barakovic, Fahir, Ilieva-Pandeva, Katya A., Kouz, Simon, Fang, Weiyi, Moura Jorge, Jose C., Ivanova, Raya, Luciardi, Hector L., de Santos, Mayler O. N., Horak, David, Nogareda, Gustavo, Airaksinen, Juhani K., Soggia, Ana Priscila, Starcevic, Boris, Posio, Pirjo, Prieto, Juan-Carlos, Lin, Xuefeng, Zhang, Xuelian, Guzman, Pablo N., Tse, Hung-Fat, Lecorps, Guillaume, Weidinger, Franz, Hoag, Gordon, Roosen, John, Pandey, Amritanshu, Lozada, Henry J. Garcia, Deloatch, Shalonda, Mentz, Robert J., Hedman, Anu, Coverdale, Steven G. M., Ke, Yuannan, Robinson, Simon, May, Ole, Matuska, Jiri, Rouleau, Jean-Lucien, Shehova-Yankova, Nina S., Sussex, Bruce, Sader, Mark, Saavedra, Silvia S., Povolny, Petr, Yang, Xinchun, Reiner, Zeljko, Faes, Dirk, Triana, Miguel A. Urina, Savard, Daniel, Shou, Xiling, Porthan, Kimmo, Florenzano, Fernando, Saporito, Wladmir, Parada, Jeffrey Castellanos, Potthoff, Sergio, Krstulovic, Stanka Mejic, Acevedo, Monica, Schiavi, Lilia B., Waites, Jonathon H., Caruso, Orlando C., Benov, Haralambi O., Yong, Huo, Senaratne, Manohara, Ducrocq, Gregory, Marin Neto, Jose A., Lomholdt, Jens D., Vijayaraghavan, Ram, Hald, Flemming, Dujardin, Karl, Raungaard, Bent, Murin, Jan, Machova, Vilma, Giuliano, Maria E., Jaramillo, Nicolas, Chua, Terrance, Novoa, Federico, Costamagna, Osvaldo, Kornder, Jan, Huang, Lan, Nahuelpan, Leonardo, Valdovinos, Pablo Carlos Montenegro, Varleta, Paola, Fernandez, Mauricio, Alan, David, Bottcher, Morten, Dran, Ricardo D., Soward, Allan, Zhu, Hong, Clemmensen, Peter, Dickey, Sheila, Pereira, Sabrina Bernardez, Tricoci, Pierluigi, Leonardi, Sergio, Fras, Zlatko, Tzekova, Maria L., Jordan, Joseph Dedrick, Rech, Rafael, Muller, Christian, Eapen, Zubin, Fernandes Manenti, Euler Roberto F., Kelsey, Sheryl F., Petranov, Stanislav L., Car, Sinisa, Viigimaa, Margus, Pintaric, Hrvoje, Dupuis, Robert, Rokyta, Richard, Nieminen, Markku S., Barbato, Emanuele, Aidar Ayoub, Jose Carlos, Leone, Attilio, Velcheva, Elena S., Peng, Daoquan, Bodanese, Luiz C., Linhart, Ales, Li, Tianchang, Giordano, Jorge A., Bourgeois, Ronald, Raffel, Owen, De Wolf, Luc, Convens, Carl, Poulsen, Steen Hvitfeldt, Tamby, Jean-Francois, Huynh, Thao, Stambuk, Kresimir, Reis, Helder J. L., Stringfellow, Kenya, Trotter, Charlene, Vulic, Dusko, Diaz, Rafael, Carnero, Gabriela S., Maia, Lilia Nigro, Povsic, Thomas J., Carroll, Patrick A., Vuurmans, Tycho, Adamkova, Vera, Alexander, Karen, Bai, Feng, Steg, Gabriel, Moreira, Humberto Graner, Aylward, Philip E., Mollov, Mihail N., Videbaek, Lars, Kimura, Takeshi, Svab, Premysl, Chiang, Chern-En   +499 more
core  

Odyssey [PDF]

, 1998
We present results obtained with the Odyssey simulation code. Odyssey is a 1, 2, and 3 dimensional AMR code using cartesian, cylindrical, and spherical coordinates.
Rathkopf, J., Brown, S., Lambert, M., Cook, G., Peters, D., Kueny, C., Braddy, D.   +6 more
core  

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source