Results 201 to 210 of about 98,650 (241)
ABSTRACT The transcription factor zinc finger protein 143 (ZNF143) plays a crucial role in regulating diverse biological processes, including cell cycle progression, development, and cellular differentiation. Similarly, c‐Myc is well‐established as a key regulator of cell proliferation, differentiation, and metabolic homeostasis.
Caifang Sun +6 more
wiley +1 more source
Early Molecular Testing for Presumptive Genetic Eye Diseases. [PDF]
Ibarra-Ramírez M +5 more
europepmc +1 more source
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source
Harnessing Patient-Generated Data for Rare Disease Knowledge Enrichment: A Pilot Study. [PDF]
Hui SWY, Chen F, Wang K, Weng C.
europepmc +1 more source
Chronic stress is associated with mTORC1 hyperactivation and autophagy‐related abnormalities, accompanied by cortical network desynchronization and accelerated amyloid pathology in a 5xFAD model with depression‐like behaviors. Pharmacological mTORC1 inhibition with EN6 ameliorates these molecular, pathological, and network abnormalities and improves ...
Yang Zou +10 more
wiley +1 more source
The Metabolic-Inflammatory Axis in Hypertrophic Cardiomyopathy. [PDF]
Ermer KJ, Sequeira V.
europepmc +1 more source
The R01 Odyssey: A Journey of Comedic Hurdles (and Science). [PDF]
Sinvani L, Gordon S, Makhnevich A.
europepmc +1 more source
ABSTRACT The recently published ONKOPEDIA guideline on myelofibrosis, issued under the auspices of the German Society of Hematology and Oncology (DGHO), provides an updated, evidence‐based framework for the diagnosis and management of this rare, chronic myeloproliferative neoplasm.
Martin Griesshammer +8 more
wiley +1 more source

