Results 41 to 50 of about 24,709 (258)

Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems

Advanced NanoBiomed Research, EarlyView.
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai, Ayushi Priyam, Ahmed Rashed, Gebreselassie Addisu Tilaye, Kamal Poudel, Aaron G. Schultz, Richard J. Williams   +6 more
wiley   +1 more source

Revised OECD Transfer pricing Guidelines and the Czech tax policy

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2011
In applying the international principles to the taxation of Multinational Enterprises, one of the most difficult issues that have arisen is the establishment for tax purposes of appropriate transfer prices.
Veronika Solilová
doaj   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Setting off on the right path: make your research regulatory relevant

Frontiers in Research Metrics and Analytics
Scientifically well-established methods do not automatically get used in regulations. Even when there is an urgent need for regulatory relevant test methods, methods need to pass through a so-called standardization process.
Anna Pohl, Elise Morel, Elise Morel, Eric A. J. Bleeker, Sean Kelly, Rachel Smith, Claus Svendsen, Thomas A. J. Kuhlbusch, Thomas A. J. Kuhlbusch, Thomas A. J. Kuhlbusch, Elisabeth Heunisch   +10 more
doaj   +1 more source

The History of National Contact Points and the OECD Guidelines for Multinational Enterprises [PDF]

Rechtsgeschichte - Legal History, 2017
This article analyses the legal development of the OECD Guidelines for Multinational Enterprises (MNE Guidelines) and their implementation mechanism – National Contact Points (NCPs).
Sander van ‘t Foort
doaj   +1 more source

Additives Enhancing Biodegradability in Plastics and Potential Implications for Textiles: A Mechanistic Review

Journal of Applied Polymer Science, EarlyView.
Mechanistic insights from additive‐assisted plastic degradation guide the design of environmentally adaptive textile fibers. Functional additives enhance oxidative, hydrolytic, enzymatic, and microbial degradation pathways. Translating these strategies requires control of fiber architecture, additive distribution, and environmental interactions ...
Julia Cunniffe, Joel Pawlak, Richard Venditti   +2 more
wiley   +1 more source

The Role of Soft Law in the Application of the Law: The Norwegian Perspective

Oslo Law Review
The article explores whether soft law instruments—such as the UN Guiding Principles on Business and Human Rights (UNGP) and OECDʼs Guidelines for Multinational Enterprises (OECD Guidelines)—have a role to play in the application of Norwegian law.
Frode Elgesem
doaj   +1 more source

Operationalizing BioSSbD: A safe‐and‐sustainable‐by‐design framework for biorefineries

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Biorefineries are central to the transition toward a circular bioeconomy; however, their increasing scale and technological heterogeneity, and the integration of biological, chemical, and thermochemical processes introduce complex challenges related to safety, sustainability, and operational reliability. Existing Safe‐and‐Sustainable‐by‐Design
Fernando Ramonet
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

The Status of OECD guidelines regarding regulatory compliance of 2D materials: a case study of graphene

Mundo Nano
The regulatory testing of graphene and other two-dimensional (2D) materials presents significant challenges due to the unique physicochemical properties of these materials.
Blanca Suarez-Merino, Luis Mauricio Ortiz Galvez   +1 more
doaj   +1 more source