Results 11 to 20 of about 19,096 (191)

The role of oestrogen and oestrogen-calcium axis in endometrial carcinoma

Gynecology and Obstetrics Clinical Medicine
Unopposed oestrogen is recognised as an inducer of endometrial cancer. Over the past 50 years, the effects of oestrogen on the endometrium and endometrial cancer have been a hot topic in the field of gynaecological oncology.
Jingyi Zhou, Jianliu Wang, Xuerun Liu
doaj   +2 more sources

Endometrial factors under treatment with oestrogen and oestrogen/progestogen combinations

, 1978
In a continuing prospective study, uterine curettage was undertaken on sixty-four patients attending a Menopause Clinic prior to consideration of gonadal hormone therapy.
Maddock, J., Aylward, Mansel, Protheroe, D. A., Ward, A., Parker, A.   +4 more
core   +6 more sources

Oestrogen metabolism in colorectal cancer [PDF]

, 2017
Colorectal cancer (CRC) is the second most prevalent cancer. Although not typically considered a hormonally responsive malignancy, oestrogens are linked to disease risk and survival.
Gilligan, Lorna Catherine
core   +6 more sources

Microarray analysis of tamoxifen resistance in breast cancer. [PDF]

, 2009
PhDTamoxifen remains a widely used hormone therapy for pre and postmenopausal women with hormone receptor positive breast cancer in both adjuvant and metastatic disease settings. Resistance to this well tolerated and cost-effective drug limits its use.
Moss, Charlotte
core   +4 more sources

Parenteral oestrogen in the treatment of prostate cancer: a systematic review. [PDF]

, 2008
The objectives of this study were to assess the effectiveness and safety of parenteral oestrogen in the treatment of prostate cancer, and to examine any dose relationship. A systematic review was undertaken.
Langley, R. E., Ritchie, G, Abel, P, Norman, G., Langley, RE, Parmar, M. K B, R E Langley, Abel, P., Dean, ME, Hodges, ZC, Sydes, M. R., P Abel, M E Dean, A J Eastwood, G Norman, Norman, G, Z C Hodges, Ritchie, G., Sydes, MR, Hodges, Z. C., Dean, M. E., Eastwood, AJ, M R Sydes, Parmar, MKB, G Ritchie, Eastwood, A. J., M K B Parmar   +26 more
core   +1 more source

Oestrogen

, 2022
This chapter explores the conceptualisation of oestrogen ‘deficit’ for women with variations in sex characteristics (VSCs), and their relationship with the biomedical replacement therapies designed to supplement or restore their hormone levels (i.e. HRT).
Jones, Charlotte, Fearon, Kriss
core   +1 more source

Immunohistochemical evaluation of oestrogen receptors α and β in epithelium of the vaginal mucous membrane in women after oestrogen therapy [PDF]

, 2017
Oestrogens act on target cells through α and β receptors (ERα and ERβ). Expression of oestrogen receptors is associated with the age and menopausal condition of women.
Lech Chyczewski, Beata Sawczuk, Maria Gołębiewska, Andrzej Mazurek   +3 more
core   +1 more source

Cell Cycle Status Influences Resistance to Apoptosis Induced by Oxidative Stress in Human Breast Cancer Cells, Which Is Accompanied by Modulation of Autophagy

Current Issues in Molecular Biology, 2023
Cancer cells are characterised by uncontrolled cell proliferation; however, some of them can temporarily arrest their cell cycle at the G0 or G1 phase, which could contribute to tumour heterogeneity and drug resistance.
Magdalena Kluska, Agnieszka Wanda Piastowska-Ciesielska, Paulina Tokarz   +2 more
doaj   +1 more source

Oestrogen-regulated protein SLC39A6: a biomarker of good prognosis in luminal breast cancer [PDF]

, 2021
PurposeThe outcome of the luminal oestrogen receptor-positive (ER +) subtype of breast cancer (BC) is highly variable and patient stratification needs to be refined.
El-Sharawy, Khloud A., Aleskandarany, M., El-sharawy, K. A., Althobiti, M., Toss, Michael S., Toss, M. S., Rakha, Emad A., Althobiti, Maryam, Green, Andrew R., Rakha, E. A., Green, A. R., Aleskandarany, Mohammed, Joseph, C., Joseph, Chitra   +13 more
core   +1 more source

A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitch

Veterinary Medicine and Science, 2022
Objective This report documents a rare case of vulvar discharge associated with exogenous oestrogen exposure in a large‐breed dog. Case description A 4‐year‐old spayed Weimaraner bitch was presented for evaluation of inappetence and intermittent ...
Francesca Ivaldi, Camille Ogdon, Firdous A. Khan   +2 more
doaj   +1 more source