Results 211 to 220 of about 1,272,638 (236)

Selective N‐Functionalization of Pyrazoles

European Journal of Organic Chemistry, EarlyView.
This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek, Matthias Schrader, Christopher J. Teskey   +2 more
wiley   +1 more source

CTRIAL-IE (ICORG) 15-34: The impact of the 21 gene breast recurrence score® assay on chemotherapy prescribing in oestrogen receptor positive, lymph node positive early stage breast cancer in Ireland. [PDF]

Ir J Med Sci
Mullally WJ, Hassan A, Keegan N, O'Leary C, McSorley L, Mahgoub T, O'Reilly S, Walshe J, Kennedy MJ, Coate L, O'Connor M, Keane M, Kelly CM, Duffy K, Murphy CG, Milewski M, Molloy S, Egan K, Murphy V, Breathnach OS, Grogan L, Hennessy BT, Morris PG.   +22 more
europepmc   +1 more source

Author Correction: Spatial heterogeneity of peri-tumoural lipid composition in postmenopausal patients with oestrogen receptor positive breast cancer. [PDF]

Sci Rep
Cheung SM, Chan KS, Zhou W, Husain E, Gagliardi T, Masannat Y, He J.   +6 more
europepmc   +1 more source

Spatial heterogeneity of peri-tumoural lipid composition in postmenopausal patients with oestrogen receptor positive breast cancer. [PDF]

Sci Rep
Cheung SM, Chan KS, Zhou W, Husain E, Gagliardi T, Masannat Y, He J.   +6 more
europepmc   +1 more source

ATF4 as a Prognostic Marker and Modulator of Glutamine Metabolism in Oestrogen Receptor-Positive Breast Cancer.

Pathobiology
Patel R, Alfarsi LH, El-Ansari R, Masisi BK, Erkan B, Fakroun A, Ellis IO, Rakha EA, Green AR.   +8 more
europepmc   +1 more source

Expression of oestrogen receptor beta (ERβ1) protein in human breast cancer biopsies [PDF]

British Journal of Cancer, 2002
Oestrogen action is mediated via specific receptors that act as ligand-activated transcription factors. A monoclonal antibody specific to the C-terminus of human oestrogen receptor beta has been characterized and the prevalence of expression of oestrogen
M R Millar, P T K Saunders
exaly   +2 more sources

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Back to the future: The impact of oestrogen receptor profile in the era of molecular endometrial cancer classification

European Journal of Cancer, 2023
Aniello Foresta, Luca Palmieri, Alessandro Petrecca   +2 more
exaly  

Structure of the ligand‐binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

EMBO Journal, 1999
Andrzej M Brzozowski, Jan-Ake Gustafsson, Roderick E Hubbard   +2 more
exaly  

Development of subtype-selective oestrogen receptor-based therapeutics

Nature Reviews Drug Discovery, 2011
Jan-Ake Gustafsson
exaly