Results 151 to 160 of about 1,274,911 (296)

Off-Design Reynolds Number Effects for a Supersonic Transport [PDF]

open access: yes
A high Reynolds number wind tunnel test was conducted to assess Reynolds number effects on the aerodynamic performance characteristics of a realistic, second-generation supersonic transport concept.
Owens, Lewis R.   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Flight comparison of the transonic agility of the F-111A airplane and the F-111 supercritical wing airplane [PDF]

open access: yes
A flight research program was conducted to investigate the improvements in maneuverability of an F-111A airplane equipped with a supercritical wing. In this configuration the aircraft is known as the F-111 TACT (transonic aircraft technology) airplane ...
Friend, E. L., Sakamoto, G. M.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Development of an On-off Sensor with Anti-interference

open access: yesGong-kuang zidonghua, 2010
In view of the problem that existing on-off sensors are easy to falsely judge in strong electromagnetic field environment to cause inaccurate monitoring, a type of on-off sensor was designed using magnetic induction principle and high anti-interference ...
ZHANG Yuan-zheng   +4 more
doaj  

Computations in turbulent flows and off-design performance predictions for airframe-integrated scramjets [PDF]

open access: yes
The research activity focused on two main tasks: (1) the further development of the SCRAM program and, in particular, the addition of a procedure for modeling the mechanism of the internal adjustment process of the flow, in response to the imposed ...
Goglia, G. L., Spiegler, E.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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