Contoured tank outlets for draining of cylindrical tanks in low-gravity environment [PDF]
An analysis is presented for defining the outlet contour of a hemispherical-bottomed cylindrical tank that will prevent vapor ingestion when the tank is drained.
Symons, E. P.
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Hydrodynamic and hydro acoustic analysis of marine propeller in off design flow conditions. [PDF]
PLoS OneNazeer A +7 more
europepmc +1 more source
The Navy/NASA Engine Program (NNEP89): Interfacing the program for the calculation of complex Chemical Equilibrium Compositions (CEC) [PDF]
The NNEP is a general computer program for calculating aircraft engine performance. NNEP has been used extensively to calculate the design and off-design (matched) performance of a broad range of turbine engines, ranging from subsonic turboprops to ...
Gordon, Sanford
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Impact of extracorporeal blood pump gap sizes on the performance and hemocompatibility under off-design operation. [PDF]
Artif OrgansFischer L +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Annual performance evaluation of a hybrid concentrated solar-micro gas turbine based on off-design simulation. [PDF]
HeliyonHosseini S +3 more
europepmc +1 more source
Development of a solar-powered residential air conditioner: System optimization preliminary specification [PDF]
Investigations aimed at the optimization of a baseline Rankine cycle solar powered air conditioner and the development of a preliminary system specification were conducted.
Hwang, K. C., Rousseau, J.
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source