Results 91 to 100 of about 272,337 (255)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Comparing the nutritional, phytochemical, and anti-microbial potential of wild and cultivated Tetragonia decumbens mill.: A promising leafy vegetable for bio-saline agriculture in South Africa

open access: yesJournal of Agriculture and Food Research
Tetragonia decumbens is a neglected edible halophyte that grows naturally in coastal areas of South Africa. Its underutilisation is due to the limited literature on its nutraceutical potential.
Avela Sogoni   +6 more
doaj   +1 more source

Assessing Crash Risks on Curves [PDF]

open access: yes, 2006
In Queensland, curve related crashes contributed to 63.44% of fatalities, and 25.17% required hospitalisation. In addition, 51.1% of run-off-road crashes occurred on obscured or open-view road curves (Queensland Transport, 2006).
Chen, Samantha   +4 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Off-road mobile robot control: An adaptive approach for accuracy and integrity [PDF]

open access: yes, 2012
International audienceThis paper proposes an algorithm dedicated to the control of off-road mobile robots at high speed. Based on adaptive and predictive principles, it first proposes a control law to preserve a high level of accuracy in the path ...
Bouton, N.   +3 more
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

A preliminary spatial analysis of diagnosed stroke disease in Osun state, Nigeria

open access: yesThe Pan African Medical Journal, 2016
INTRODUCTION: there have been a number of clinical studies on diagnosed Stroke disease. However, there have been few studies on the geographical disparities for stroke.
Ayila Emmanuel Adzandeh   +2 more
doaj   +1 more source

Multifunctional mover on the principle of combined segavereline [PDF]

open access: yes, 2017
The description of the principle of combined aguirregaray and propulsion from versatile road and off-road support-geometric permeability, implementing the most economical mode in terms of specific fuel consumption and reduced environmental load ...
Мехренцев, А. В.   +2 more
core  

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

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