Results 171 to 180 of about 1,681,289 (373)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A Perception Survey of Lean Management Practices for Safer Off-Site Construction
BuildingsLean practice is recognised for having a great potential in promoting safety risk management in off-site construction (OSC). This paper presents results of a study conducted to assess the impact of lean practice on safety risk management in OSC in a ...
Wakisa Simukonda, Fidelis Emuze
doaj +1 more source
Automatic generation of progress profiles for eathwork operations using 4D visualisation model [PDF]
Despite of the advances in construction planning and scheduling software, construction managers and planners are still facing problems in achieving accurate planning, scheduling and costing due to the one-off nature of the construction projects and the ...
Castro, S, Dawood, N, Shah, RK
core
Drywall finishing with collaborative robot arm in off-site construction [PDF]
Philippe D'Amours +3 more
openalex +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Journal of Cleaner Production, 2023 Liang Wang, Yueqiao Zhao, Xianfei Yin
semanticscholar +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Evaluating site induction practice efficiency and effectiveness:an organisational case study [PDF]
, 2017 The style of induction presentation and other processes, irrespective of duration, immediately establishes the context and attitude of the construction site team and is where initial behavioural standards are established.
Blackwood, David +4 more
core