The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway. [PDF]
Shi G, Zhang Z.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert. [PDF]
Gao X, Cai Y, An R.
europepmc +1 more source
[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells. [PDF]
Zhang Y +10 more
europepmc +1 more source
[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial-mesenchymal transition by forming a positive feedback loop with c-Myc. [PDF]
Tang Y, Ji F.
europepmc +1 more source
Retraction: Towards robot-assisted therapy for children with autism-the ontological knowledge models and reinforcement learning-based algorithms. [PDF]
Frontiers Editorial Office.
europepmc +1 more source
[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome. [PDF]
Li L, Dong L, Zhao D, Gao F, Yan J.
europepmc +1 more source
Correction: Comparing pregnancy outcomes in a population with natural versus surgical reduction of twin pregnancies: a retrospective cohort study. [PDF]
Frontiers Production Office.
europepmc +1 more source

