Results 51 to 60 of about 6,730,175 (246)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure [PDF]

Introduction: Blood pressure (BP) is a highly heritable trait with over 2000 underlying genomic loci identified to date. Although the kidney plays a key role, little is known about specific cell types involved in the genetic regulation of BP.Methods ...
de Borst, Martin, International Consortium of Blood Pressure; Soroush Sardari, de Borst, M, Koskinen, Seppo, Sardari, S, Vaez, A, International Consortium of Blood Pressure, de Borst, Martin; id_orcid, Snieder, H, Gow, Alan J.; id_orcid, Snieder, Harold, ?, ?, Kamali, Z, Ganji-Arjenaki, M, Ganji-Arjenaki, Mahboube, Snieder, Harold; id_orcid, Kamali, Zoha; id_orcid, Sardari, Soroush, Vaez, Ahmad, Vaez, Ahmac, et al., Kamali, Zoha   +21 more
core   +1 more source

A Modern Method to Monitor Office Blood Pressure

INNOVATIONS in Pharmacy, 2017
The diagnosis and management of hypertension relies on accurate and precise blood pressure (BP) measurements and monitoring techniques. Variability in traditional office based BP readings can contribute to misclassification and potential misdiagnosis of ...
Emiliya Khazan, Augustus Hough
doaj   +1 more source

The long-term reproducibility of the white-coat effect on blood pressure as a continuous variable from the Ohasama Study

Scientific Reports, 2023
There is little information about the reproducibility of the white coat effect, which was treated as a continuous variable. To investigate a long-term interval reproducibility of the white-coat effect as a continuous variable.
Michihiro Satoh, Tomoya Yoshida, Hirohito Metoki, Takahisa Murakami, Yukako Tatsumi, Takuo Hirose, Kyosuke Takabatake, Megumi Tsubota-Utsugi, Azusa Hara, Kyoko Nomura, Kei Asayama, Masahiro Kikuya, Atsushi Hozawa, Yutaka Imai, Takayoshi Ohkubo   +14 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Ambulatory systolic blood pressure predicts left ventricular mass in type 2 diabetes, independently of central systolic blood pressure

, 2012
Objectives: Both ambulatory and central blood pressures have been reported to correlate more closely than office blood pressure with left ventricular mass index (LVMI).
Länne, Toste,, Östgren, Carl Johan,, Nyström, Fredrik,, Wijkman, Magnus,, Grodzinsky, Ewa,, Engvall, Jan,   +5 more
core   +1 more source

Agreement Between Guideline Thresholds Using an “All‐in‐One” Device to Measure Office, Home, and Ambulatory Blood Pressures

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Blood pressure (BP) thresholds for diagnosing and managing hypertension vary for office, home, and ambulatory readings, and between guideline documents.
Kazuomi Kario, Naoko Tomitani, Satoshi Hoshide, Masafumi Nishizawa, Tetsuro Yoshida, Tomoyuki Kabutoya, Takeshi Fujiwara, Hiroyuki Mizuno   +7 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source