Results 61 to 70 of about 1,676 (211)

Requirements for professional office blood pressure monitors

Journal of Hypertension, 2012
For more than half a century measurement of blood pressure in the doctor's office using a mercury sphygmomanometer and the auscultatory method has been the cornerstone for hypertension management. However, due to the environmental and service issues mercury devices will not be available in the near future.
Stergiou, GS, PARATI, GIANFRANCO, Asmar, R, O’Brien, E, on behalf of the European Society of Hypertension Working Group on Blood Presuure Monitoring   +4 more
openaire   +4 more sources

Office Blood Pressure Measurement [PDF]

Hypertension, 2018
See related article, pp 848–857 For almost a century, office blood pressure (OBP) measurement has been regarded as the cornerstone for diagnosis and management of hypertension because the vast majority of the evidence on the risks associated with elevated BP and the benefits of treatment-induced BP lowering has been based on OBP measurements. However,
Stergiou, George, Kollias, Anastasios, Parati, Gianfranco, O'Brien, Eoin   +3 more
openaire   +4 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Automated Office Blood Pressure Measurements in Waiting Room or Isolated Room for Diagnosis and Phenotyping of Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Automatic office blood pressure measurement (AOBPM) in the waiting room could improve the performance of diagnosing hypertension without requiring an isolated room to carry out exploration.
Marisol Sánchez Bacaicoa, Sergio Rico, Alejandra Gullón, Jacinto Fernandez Pardo, Juan Villa, Eva Nadiejda, Roberto Robles, Jose M. del Aguila, Pedro Cunha, Valentina Vassilenko, Enrique Rodilla, Juan F. Sánchez Muñoz‐Torrero   +11 more
doaj   +1 more source

Aggressive renal sympathetic denervation approach to treating resistant hypertension: A fresh start?

Artery Research, 2016
A multivariable analysis identified predictors of systolic blood pressure change in SYMPLICITY HTN-3 trial. Additional analyses examined the influence of medication changes, results in selected subgroups and procedural factors.
Márcio Galindo Kiuchi, Luis Marcelo Rodrigues Paz, Shaojie Chen   +2 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Analysis of the Accuracy of Unattended Automated Blood Pressure Measurements and Control of Blood Pressure Thresholds: A Multicenter Cross‐Sectional Study

The Journal of Clinical Hypertension
Accurate blood pressure measurement is fundamental for the diagnosis and management of hypertension. The emergence of u‐AOBP has been proposed as a potential alternative or complementary approach for assessing patients’ blood pressure status within ...
Shijie Yang, Zhanyang Zhou, Huanhuan Miao, Zhen Yin, Xiaochun Duan, Yuqing Zhang   +5 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source