Results 91 to 100 of about 1,689,880 (296)

Knowledge and Prevention of Sexually Transmitted Infections among University Students in Butembo City

Health Research in Africa
RÉSUMÉ Introduction. Sexually transmitted infections (STIs) are infections that are typically transmitted through sexual activity, including vaginal, anal, and oral sex. Young people, including university students, are particularly affected.
Kambale Mastaki J, Kambale Saruti A, Mutume Kabila T, Kanyamanda Paluku J, Kihimba Ngwalangwala, Kavira Zawadi M, Munzombo Tsongo T   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

legislación gremial y prácticas gremiales: Los artesanos de pasto (1796 - 1850).

Historia Crítica, 2003
Authors interested in the late 18th century Bourbon reforms have paid quite a lot of attention to both the Enlightenment ideal and to the economic and administrative measures implemented by the Spanish empire in the context of the so-called “defensive ...
Maria Fernanda Duque.
doaj  

Criminal liability for interfering with the legal professional activities of journalists (art. 171 of the Criminal Code): a scientific and practical comment

Науково-інформаційний вісник Івано-Франківського університету права імені Короля Данила Галицького
Purpose. Scientific and practical commentary on certain provisions of Art. 171 of the Criminal Code of Ukraine. In order to achieve the declared goal, an appropriate methodology was chosen, in particular, philosophical, general scientific and ...
Movchan R., Hel A.
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Dampak Edukasi Gizi Olahraga Bagi Atlet, Pelatih dan Official Binaraga Papua

Multilateral: Jurnal Pendidikan Jasmani dan Olahraga
Atlet binaraga rentan terhadap kelebihan asupan energi dan protein serta penggunaan suplemen yang tidak tepat. Tujuan dari penelitian ini adalah mengetahui dampak edukasi gizi olahraga bagi atlet, pelatih dan official binaraga Papua.
Evi Sinaga, Saharuddin Ita, Yohanis M. Mandosir, Miftah Fariz Prima Putra, Daniel Womsiwor, Kurdi Kurdi, Ewendi W. Mangolo, Tri Setyo Guntoro, Eva Sinaga, Dewi Oktavia Sinaga   +9 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Minute by Minute: The Problem of Officials in Official History

Diplomacy & Statecraft
This article explores a persistent dilemma in official history: whether officials should be protected from the loss of anonymity when their confidential advice is published. Since FOI (2000) the problem has recurrd,from its interwar precedent with the publication of British Documents on the Origins of the War (1926–38). Its most controversial voice was
openaire   +2 more sources