Results 81 to 90 of about 1,377,987 (310)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Iraqi Official Gazette 1985-English
Alwaqai Aliraqiya: The Official Gazette of the Republic of ...
Ministry of Justice, Republic of Iraq
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Iraqi Official Gazette 1987-English
Alwaqai Aliraqiya: The Official Gazette of the Republic of ...
Ministry of Justice, Republic of Iraq
core
ON CORRUPTION AND ANTI-CORRUPTION CAMPAIGN IN RUSSIA
The complex of anti-corruption legislation adopted in the recent years by the Russian Federation state bodies did not significantly influence the results of corruption counteraction in our country. The article gives statistical data for corruption crimes
A. U. Dikayev
doaj
Official language, official names?
The pending officialisation of South African Sign Language (SASL) as one of South Africa’s twelve official language raises critical questions about its standardisation, application in official domains, and the recognition of SASL place names. Place-name planning, a subset of corpus planning, gains relevance as the Deaf communities uniquely assign ...
Jani de Lange +2 more
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Iraqi Official Gazette 1986-English
Alwaqai Aliraqiya: The Official Gazette of the Republic of ...
Ministry of Justice, Republic of Iraq
core
Objective: to analyze the problems existing in the modern law enforcement practice, related to the implementation of criminal-legal norms, stipulated in Article 291 and 2911 of the Russian Criminal Code (hereinafter CC of RF), to offer the authors ...
A. S. Sentsov, V. A. Volkolupova
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

