Results 81 to 90 of about 1,377,987 (310)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Iraqi Official Gazette 1985-English

open access: yes, 1985
Alwaqai Aliraqiya: The Official Gazette of the Republic of ...
Ministry of Justice, Republic of Iraq
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Iraqi Official Gazette 1987-English

open access: yes, 1987
Alwaqai Aliraqiya: The Official Gazette of the Republic of ...
Ministry of Justice, Republic of Iraq
core  

ON CORRUPTION AND ANTI-CORRUPTION CAMPAIGN IN RUSSIA

open access: yesRussian Journal of Economics and Law, 2012
The complex of anti-corruption legislation adopted in the recent years by the Russian Federation state bodies did not significantly influence the results of corruption counteraction in our country. The article gives statistical data for corruption crimes
A. U. Dikayev
doaj  

Official language, official names?

open access: yes
The pending officialisation of South African Sign Language (SASL) as one of South Africa’s twelve official language raises critical questions about its standardisation, application in official domains, and the recognition of SASL place names. Place-name planning, a subset of corpus planning, gains relevance as the Deaf communities uniquely assign ...
Jani de Lange   +2 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Iraqi Official Gazette 1986-English

open access: yes, 1986
Alwaqai Aliraqiya: The Official Gazette of the Republic of ...
Ministry of Justice, Republic of Iraq
core  

ISSUES OF QUALIFICATION OF BRIBE GIVING AND MEDIATION IN BRIBERY IN THE MODERN LAW-ENFORCEMENT PRACTICE

open access: yesRussian Journal of Economics and Law, 2016
Objective: to analyze the problems existing in the modern law enforcement practice, related to the implementation of criminal-legal norms, stipulated in Article 291 and 2911 of the Russian Criminal Code (hereinafter CC of RF), to offer the authors ...
A. S. Sentsov, V. A. Volkolupova
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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