Results 141 to 150 of about 1,689,880 (296)

The Blind Spot of Small-Sided Games: Missing High-Intensity Deceleration Demands in Elite Soccer Players. [PDF]

Sports (Basel)
Manzi V, Di Lascio G, Taleb M, Giardullo G, Laterza F, Savoia C, Caminiti G, D'Onofrio R, Raiola G.   +8 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Inter-Slice Representation Outweighs Bounding-Box Supervision Extent in Lightweight 2.5D Pulmonary Nodule Detection: A Whole-Volume Benchmark on LUNA16. [PDF]

Diagnostics (Basel)
Chou LF, Peng BR, Chien SW, Huang YM.
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Admission-cohort differences in physical fitness, weight status, and fitness-standard failure among first-year students at a single vocational college in Shanxi Province, China. [PDF]

Front Public Health
Hong J.
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

official NASA photo (back)

, 1967
This image reflects a view of the back side of William Thornton's official NASA ...

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Transferability of Intra- and Inter-Sectoral Coordination Between Training Tasks and Official Matches in Semi-Professional Football Players. [PDF]

J Funct Morphol Kinesiol
Maio E, Teixeira JE, Branquinho L, Silva AJ, Forte P, Ferraz R.   +5 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The Economic Returns to the Knowledge and Use of a Second Official Language: English in Quebec and French in the Rest-of-Canada [PDF]

In a country with two official languages, such as Canada, the demand for bilingualism may lead individuals born with one mother tongue to acquire the second official language.
Louis N. Christofides, Robert Swidinsky
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