Results 201 to 210 of about 1,067,197 (307)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Training without jobs is a waste of aid: why Japan's partnership with the World Bank must tackle the 'fiscal space' for health workforce. [PDF]

BMJ Glob Health
Kubota K.
europepmc   +1 more source

Polish official assistance for developing countries

Contemporary Europe, 2014
openaire   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Unstable aid, unstable lives: a call for reinforced global health solidarity. [PDF]

Front Public Health
Chitrakar SB, Choi JW, Kim KH.
europepmc   +1 more source

Japan's Official Development Assistance : Promoting Sustainable Development

Japan's Official Development Assistance : Promoting Sustainable Development
P(論文) http://www.kawasaki-m.ac.jp/soc/mw/journal/en/2002-e08-2/5_kamigwi ...
openaire  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Impact of US government funding freezes on the HIV response: findings from a rapid survey in 32 countries. [PDF]

Health Aff Sch
Brazier E, Duda SN, Ross J, Semeere AS, Tiendrebeogo T, Chimbetete C, Nash D.   +6 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Comment for conflict and health don't let sexual and reproductive health in humanitarian and fragile settings become a casualty of aid cuts and crisis fatigue. [PDF]

Confl Health
Tran NT, Talbi N, Hildebrand M, Cornier N, Khosla R, Schulte-Hillen C.   +5 more
europepmc   +1 more source