Results 51 to 60 of about 43,003 (262)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Inversion of Glacier 3D Displacement from Sentinel-1 and Landsat 8 Images Based on Variance Component Estimation: A Case Study in Shishapangma Peak, Tibet, China

open access: yesRemote Sensing, 2022
Offset tracking technology is widely studied to evaluate glacier surface displacements. However, few studies have used a cross-platform to this end. In this study, two heterogeneous data sources, Sentinel-1 and Landsat 8, from January 2019 to January ...
Chengsheng Yang   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Coseismic Deformation Field of the Mw 7.3 12 November 2017 Sarpol-e Zahab (Iran) Earthquake: A Decoupling Horizon in the Northern Zagros Mountains Inferred from InSAR Observations

open access: yesRemote Sensing, 2018
The study of crustal deformation fields caused by earthquakes is important for a better understanding of seismic hazard and growth of geological structures in tectonically active areas.
Sanaz Vajedian   +7 more
doaj   +1 more source

Parsimonious cooperative distributed MPC algorithms for offset-free tracking [PDF]

open access: yesJournal of Process Control, 2017
Abstract We propose in this paper novel cooperative distributed MPC algorithms for tracking of piecewise constant setpoints in linear discrete-time systems. The available literature for cooperative tracking requires that each local controller uses the centralized state dynamics while optimizing over its local input sequence.
Razzanelli, Matteo, Pannocchia, Gabriele
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Target Tracking Based on Correlation Filter for Scale Offset

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
AbstractExisting scale estimation methods mainly use fixed-size tracking box for target tracking. However, when the moving direction of the target changes from near to far or from far to near, the size of the current tracking box cannot adapt to the scale change.
Jianhao Tan, Xiaoping Ma, Yaonan Wang
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Retrieving 3-D Large Displacements of Mining Areas from a Single Amplitude Pair of SAR Using Offset Tracking

open access: yesRemote Sensing, 2017
Due to the side-looking imaging geometry of the current synthetic aperture radar (SAR) sensors, only ground deformation along the radar’s line-of-sight (LOS) and azimuth directions can be potentially obtained from a single amplitude pair (SAP) of SAR ...
Zefa Yang   +7 more
doaj   +1 more source

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