Safety and Pharmacokinetics of Multiple Doses of Intravenous Ofloxacin in Healthy Volunteers [PDF]
, 1992 The safety and pharmacokinetics of ofloxacin in 48 healthy male volunteers were studied in a two-center, randomized, double-blind, placebo-controlled study.
Flor, Soledad +5 more
core +3 more sources
Topical azithromycin or ofloxacin for endophthalmitis prophylaxis after intravitreal injection. [PDF]
, 2014 Background: The number of patients who have undergone intravitreal injections has increased enormously in recent years, but a consensus is still lacking on prophylaxis for endophthalmitis.
Arias Barquet, Lluís +4 more
core +2 more sources
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance. [PDF]
, 2018 Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available datasets describing its AMR characteristics demand disparate data-type analyses ...
Anand, Amitesh +11 more
core +2 more sources
Brazilian Journal of Pharmaceutical SciencesThe present research work was envisaged to develop bilayer tablets to improve therapeutic efficacy of antibiotic combination for the treatment of sexually transmitted diseases. The combination of two antibiotics i.e.
Swati Sanjay Gaikwad +3 more
doaj +1 more source
Analysis of Relationship between Levofloxacin and Corrected QT Prolongation Using a Clinical Data Warehouse [PDF]
Healthcare Informatics Research, 2011 ObjectiveThe aim of this study was to examine whether or not levofloxacin has any relationship with QT prolongation in a real clinical setting by analyzing a clinical data warehouse of data collected from different hospital information systems ...
Man Young Park +7 more
doaj +1 more source
Determination of Pharmaceuticals in Coastal Systems Using Solid Phase Extraction (SPE) Followed by Ultra Performance Liquid Chromatography – tandem Mass Spectrometry (UPLC-MS/MS) [PDF]
, 2015 This paper describes the optimization and validation of an analytical method for the determination of 83 pharmaceutically active compounds (PhACs) in aqueous samples using solid-phase extraction (SPE) followed by ultra performance liquid chromatography ...
Baena Nogueras, Rosa María +3 more
core +1 more source
Ofloxacin resistance in Mycobacterium tuberculosis: An increasing concern
Indian Journal of Health Sciences and Biomedical Research KLEU, 2021 Multidrug resistance tuberculosis (MDR-TB) associated with the development of resistance to fluoroquinolones (FQs) especially ofloxacin is a matter of concern, as they had been earlier recommended drugs for usage in the MDR-TB treatment regimens, and ...
Ramesh S Kumar +3 more
doaj +1 more source
Internal Medicine, 1995 We describe a patient with hypersensitivity vasculitis due to ofloxacin therapy; the vasculitis was associated with elevated transaminase and IgA levels. Cyclophosphamide and intravenous pulse prednisolone resulted in clinical improvement.
Murat Sungur +4 more
openaire +3 more sources
Immunologic Evaluation of Ofloxacin Hypersensitivity [PDF]
Allergy, Asthma & Immunology Research, 2012 Quinolone hypersensitivity, most of which is immediate type, is rare but has increased in recent years. The pathogenic mechanisms underlying immediate reactions are not defined clearly. This study was aimed to observe the clinical characteristics of immediate hypersensitivity to ofloxacin and to investigate the pathogenic mechanism with detection of ...
Young-Hee Nam +7 more
openaire +3 more sources
The significance of hazardous chemicals in wastewater treatment works effluents [PDF]
, 2012 This is the post-print version of the final paper published in Science of The Total Environment. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Aquacheck Bury UK +43 more
core +1 more source