Results 21 to 30 of about 7,313 (168)

Evaluation of optical genome mapping for detecting chromosomal translocation in clinical cytogenetics

open access: yesMolecular Genetics & Genomic Medicine, 2022
Background Balanced reciprocal translocation is one of the most common chromosomal abnormalities in humans that may lead to infertility, recurrent pregnancy loss, or having children with physical or mental abnormalities.
Peng Dai   +7 more
doaj   +1 more source

La petite histoire des OGM [PDF]

open access: yes, 2020
Les humains modifient génétiquement les organismes vivants depuis plus de 30 000 ans mais le concept des Organismes Génétiquement Modifiés ou OGM est apparu beaucoup plus récemment avec l'apparition de techniques de laboratoire permettant de manipuler ...
Montet, Didier
core  

Overgeneral autobiographical memory (phenomenon, mechanisms, empirical research) [PDF]

open access: yesСовременная зарубежная психология, 2018
In the last several years the role of overgeneral autobiographical memory (OGM) has been widely discussed in scientific articles as a factor in the appearance and chronification of depressive disorders. The present article describes the phenomenon of OGM
Pugovkina O.D.
doaj   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

open access: yesAdvanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Optical genome mapping in myelofibrosis: enhancing prognostic accuracy through high-resolution genomic profiling

open access: yesBlood Advances
: Accurate genomic stratification is essential for guiding therapeutic decisions in myelofibrosis (MF), particularly regarding allogeneic stem cell transplant.
Álvaro Díaz-González   +24 more
doaj   +1 more source

La comunicación de los alimentos genéticamente modificados: estado, regulación y lecciones

open access: yesRevista Española de Comunicación en Salud, 2020
Los organismos genéticamente modificados (OGM) constituyen un concepto equívoco y diferencialmente definido por las distintas legislaciones y sensibilidades que está presente en nuestro léxico desde hace más de 30 años. Con un campo semántico tecnológico
Gerardo Carrera Castaño
doaj   +1 more source

Feasibility of Optical Genome Mapping in Cytogenetic Diagnostics of Hematological Neoplasms: A New Way to Look at DNA

open access: yesDiagnostics, 2023
Optical genome mapping (OGM) is a new genome-wide technology that can reveal both structural genomic variations (SVs) and copy number variations (CNVs) in a single assay.
Nicoletta Coccaro   +14 more
doaj   +1 more source

Optical Genome Mapping for the Molecular Diagnosis of Facioscapulohumeral Muscular Dystrophy: Advancement and Challenges

open access: yesBiomolecules, 2023
Facioscapulohumeral muscular dystrophy (FSHD) is the second most common muscular dystrophy in adults, and it is associated with local D4Z4 chromatin relaxation, mostly via the contraction of the D4Z4 macrosatellite repeat array on chromosome 4q35.
Stephanie Efthymiou   +20 more
doaj   +1 more source

Synthesis of β‐ and γ‐Carbolinones Through a Fe(III)‐Mediated Radical 6‐Endo‐Trig Cyclization of Indole‐Based Ugi 4‐CR Adducts

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A practical strategy for synthesizing β‐ and γ‐carbolinones from indole‐based Ugi 4‐CR adducts through an intramolecular radical cyclization using Fe(III)–H species is presented. This approach enables the efficient synthesis of spiro‐carbolinones under mild reaction conditions and demonstrates the effectiveness of secondary radicals in both cyclization
María F. Olvera‐Granados   +1 more
wiley   +1 more source

DOGMA: de novo assembly of densely labelled optical DNA maps using a matrix profile approach.

open access: yesPLoS ONE
In optical genome mapping (OGM), large numbers of individual DNA maps-sequence-specific data series along single DNA molecules-are produced. Such individual maps have to be stitched together in a process called de novo OGM assembly in order to create ...
Albertas Dvirnas   +8 more
doaj   +1 more source

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